Patents Represented by Attorney Frank Chow

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  • Renin-inhibitory pepstatin phenyl derivatives
    Patent number: 4874745
    Abstract: A phenyl derivative of pepstatin A, which is much more potent than pepstatin in inhibiting renin enzyme activity and has significantly greater selectivity for renin over pepsin inhibition than does pepstatin, which is useful in treating hypertension and congestive heart failure.
    Type: Grant
    Filed: October 1, 1987
    Date of Patent: October 17, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Leeyuan Huang, Lawrence Koupal, Joseph Dunn, Jr., Jerrold M. Liesch, Otto Hensens, H. Boyd Woodruff