Abstract: There are presented compounds of the formula ##STR1## wherein R.sup.1 is a lower alkyl group, R.sup.2 is a hydrogen atom or a lower alkyl group, R.sup.3 is a hydrogen or halogen atom, R.sup.4 is a hydrogen atom or a group of the formula R.sup.5 --CO--,R.sup.6 R.sup.7 N--O--, ##STR2## A is a lower alkylene group, X is an oxygen or sulphur atom or a group of the formula >N--.sup.8 , R.sup.5 is a lower alkyl or lower haloalkyl group, R.sup.6 is a hydrogen atom or a lower alkyl group, R.sup.7 is a lower alkyl group and R.sup.8 is a hydrogen atom or a lower alkyl or lower hydroxyalkyl group, and their pharmaceutically acceptable acid addition salts.The compounds have aldosterone-antagonistic properties and are accordingly suitable for the control or prevention of heart failure, hepatic ascites, primary aldosteronism and idiopathic hypertension.

Abstract: A dual wavelength spectrophotometer for ampoule content inspection, in particular for ampoule leak detection wherein leaks are initially "flagged" via the dye bath immersion technique. Light transmitted through the ampoule is received by a bifurcated fiber optic cable providing via a random mix arrangement substantially identical ampoule optical signature signals. Each is directed through preselected interference filters, chosen on the one hand on the basis of the dye being used and the glass ampoule and its contents on the other hand. Associated with the filters are respective photodetectors, the output signals of which are connected to a difference amplifier stage. The output (if any) of the latter is compared to a preestablished (dye) threshold signal, which represents the minimum level (of dye) from which to effect a reject status. The ampoule contents or a particular component thereof may also be investigated in this manner.

Abstract: A compound of the formula ##STR1## and its pharmaceutically acceptable salts are disclosed. The compound exhibits antibacterial activity, antimalarial activity, has activity as a growth promotant for ruminants and as an agent in the treatment of swine dysentery. Also provided is a process to produce the novel compound.

Abstract: Novel 1,4-benzodiazepine derivatives, bearing between positions 1- and 2- a thiazolo or oxathiazepino ring, methods for their preparation and novel intermediates employed in these processes are disclosed. These 1,2-heterocyclic-1,4-benzodiazepines are useful as muscle-relaxant, anti-convulsant and sedative agents.