Abstract: A compound is described. The compound has the formula (Ia) as presented in the FIG. 1; wherein: X is a ring having at least 4 atoms in the ring; K is hydrocarbyl group; Rh1 is an optional halo group; Rh2 is an optional halo group; at least one of Rh1 and Rh2 is present; Rs is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group. The compound is capable of inhibiting steroid sulphatase (STS) activity.
Type:
Grant
Filed:
June 7, 2002
Date of Patent:
February 22, 2005
Assignee:
Sterix Limited
Inventors:
Michael John Reed, Barry Victor Lloyd Potter, Hatem Hejaz, Atul Purohit