Patents Represented by Attorney Frommer Lawrence & Hung, LLP.
  • Patent number: 6017542
    Abstract: Disclosed and claimed are nucleotides for genes encoding the canine herpesvirus (CHV) gB, gC and gD homologues. These genes encode polypeptides of 879, 459 and 345 amino acids, respectively, which are also disclosed and claimed. The genes are useful as DNA probes or, for preparing PCR primers. The polypeptides are useful in antigenic, immunological or vaccine compositions. The nucleotides can be expressed in any suitable vector system, allowing for production of the polypeptides. Additionally, the vector system containing any or any combination of the nucleotides can be employed in an antigenic, immunological or vaccine composition, such as a poxvirus vector system, e.g., a CHV-vaccinia or avipox virus recombinant, as can the products from expression, i.e., the gB, gC and gD glycoproteins. Antibodies elicited by the glycoproteins or from expression of the vector containing the nucleotide(s) are also useful. Methods for making and using the composition are also disclosed and claimed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 25, 2000
    Assignee: Virogenetics Corporation
    Inventors: Enzo Paoletti, Keith J. Limbach
  • Patent number: 5917873
    Abstract: A PCR is detected from a bit stream by a PCR extracting circuit. When the time reference value is detected, an STC counter counts a clock oscillated by a VCO and compares the value of the STC counter and the value of the PCR. The phase difference is fed back to the VCO through a digital filter. In the control start stage, the gain of the digital filter is designated to a large value. Thus, the phase difference is quickly converged to the allowable difference range. In the lock stage, the gain is designated to a small value. Thus, the control operation is stably performed. In the nearly unlock stage, the gain is designated to a middle value. Thus, the phase difference is quickly pulled to the allowable difference range.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: June 29, 1999
    Assignee: Sony Corporation
    Inventors: Shoji Shiomoto, Hirofumi Yuchi