Patents Represented by Attorney, Agent or Law Firm Fulbright & Laworski, LLP
  • Recombinant blood-coagulation proteases
    Patent number: 6277618
    Abstract: The invention relates to a non-glycosylated protein with enzymatic and serin protease activity, the zymogenous form thereof comprising the following domains of a protease of the factor IX family: (a) a catalytic domain, N-terminal bonded with (b) a zymogenous activation domain, N terminal bonded with (c) a EGF1 and/or EGF2 domain. Said protein can be used in a same way as the natural serine proteases of the factor IX family.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: August 21, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Erhard Kopetzki, Karl-Peter Hopfner