Abstract: The present invention relates to a substantially dry, disposable, personal cleansing article useful for both cleansing the skin or hair and delivering skin care actives onto the skin or hair. These articles are used by the consumer by (i) wetting the dry article with water and (ii) generating lather by subjecting the wetted article to mechanical forces, e.g., rubbing. The article comprises a water insoluble substrate, a lathering surfactant, and a skin care active component. Preferably, the articles of the present invention further comprise a deposition aid and/or a conditioning component.

Abstract: Cosmetic composition for topical application to the skin comprising a hydroxyalkyl cyclodextrin, salicylic acid or salicylic acid derivative and water. The compositions herein provide improved anti-acne/anti-inflammatory activity together with reduced skin irritation.

Abstract: Disclosed are cosmetic compositions, including lipsticks, comprising from 0.01% to about 50%, by weight, of cylindrical crystalline vitamin B3 particles having a particle size distribution such that at least about 70% of the crystalline particles have a height to width ratio greater than 1; from about 1% to about 90%, by weight, of an emollient component; from about 1% to about 90%, by weight, of a solidifying agent; and from about 1% to about 90%, on an anhydrous basis, of a color. The compositions provide improved skin feel of crystalline vitamin B3 compounds when applied to skin.

Abstract: The present invention relates to antimicrobial compositions which provide enhanced immediate as well as residual anti-viral and antibacterial efficacy. The antimicrobial compositions of the present invention provide previously unseen residual effectiveness against Gram negative bacteria, Gram positive bacteria, and viruses, fungi, and improved immediate germ reduction upon use. These compositions comprise: a) a safe and effective amount of a benzoic acid analog; b) a safe and effective amount of a metal salt; and c) a dermatologically acceptable carrier for the acid and salt wherein said composition has a pH of from about 1 to about 7. The invention further relates to methods of use for the present compositions as well as antimicrobial products which incorporate the compositions.

Abstract: The present invention relates to a modified polypeptide which has an enzymatic activity level of greater than about 70% of the parent polypeptide and an allergenic response level of less than about 33% of the parent polypeptide. Embodiments of the present invention relate to modified polypeptides with reduced allergenicity and high enzymatice activity comprising the formula: A-Bn wherein A is an enzyme, and mixtures thereof; B is a twin polymer moiety, having a total molecular weight of from about 0.5 kilodaltons (KD) to about 40 KD, having the formula conjugated to the enzyme; wherein R1 and R2 are essentially straight chain polymers, having a molecular weight ranging from about 0.

Abstract: The present invention relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of a composition comprising: a) a safe and effective amount of farnesol; and b) a dermatologically-acceptable carrier for the farnesol. In additional embodiments, the above composition is suitable for thickening skin and preventing and/or retarding atrophy of mammalian skin, preventing and/or retarding the appearance of spider vessels and/or red blotchiness on mammalian skin, preventing and/or retarding the appearance of dark circles under the eye of a mammal, preventing and/or retarding sallowness of mammalian skin, preventing and/or retarding sagging of mammalian skin, softening and/or smoothing lips, hair and nails of a mammal, and preventing and/or relieving itch of mammalian skin.

Abstract: The present invention relates to disposable, personal cleansing articles useful for cleansing the skin or hair. These articles are used by the consumer by wetting the dry article with water and then rubbing the article against the skin or hair. The article comprises a water insoluble substrate having a cleansing surface that contains apertures of a certain size and frequency, and a lathering surfactant releasably associated with the substrate. Preferably, the articles of the present invention further comprise a conditioning component.

Abstract: The present invention relates to a substantially dry, disposable personal cleansing article comprising: a) a water insoluble substrate comprising: 1) a first layer which exhibits a Loft-Soft Ratio of greater than about 1.1; 2) a second layer, disposed adjacent to said first layer, wherein said second layer exhibits a Loft-Soft Ratio of less than about 1.2; b) a cleansing component disposed adjacent to said first and second layers, wherein said component comprises from about 10% to about 1000%, by weight of the water insoluble substrate, of a lathering surfactant. The present invention further relates to a substantially dry, disposable personal care article suitable for conditioning wherein the above-described article comprises a therapeutic benefit component, disposed adjacent to said water insoluble substrate, wherein said component comprises from about 10% to about 1000%, by weight of the water insoluble substrate, of a therapeutic benefit component in addition to or in lieu of the cleansing component.

Abstract: A cosmetic composition in the form of a water-in-oil emulsion comprising: (a) continuous oil phase; and (b) discontinuous aqueous phase; and (c) amino acid salt of salicylic acid or salicylic acid derivative. The compositions of the invention provide regulation of the oily and/or shiny appearance of the skin.

Abstract: The subject invention relates to a water-in-silicone gel composition for skin lightening comprising: a) a safe and effective amount of a compound of formula (I), wherein Z is oxygen or sulfur; b) a mixture of dimethicone copolyol surfactant and cyclomethicone; and c) a cosmetically-acceptable carrier for said compound of formula (I) and said mixture.

Abstract: A cosmetic make-up composition suitable for use as a mascara or the like and which is in the form of an emulsion comprising an insoluble polymeric material in an aqueous emulsion; and lipophilic oil components including a polyvinylpyrrolidone hexadecane copolymer. The compositions exhibit improved wear and water resistance and are removable with soap and water.

Abstract: The present invention relates to leave-on hair styling compositions comprising from greater than 0.5% to about 5% of a water soluble, non-polymeric mineral salt, from about 0.05% to about 0.5% of a lipophilic material, from about 0.01% to about 0.5% of a surfactant, and an aqueous carrier. The surfactant is selected from the group consisting of amphoteric surfactants, anionic surfactants, and nonionic surfactants having the formula or R1R2R3Z→O, and mixtures thereof. The compositions comprise less than 0.01% cationic surfactant, less than about 0.2% of a chemical protein modifying agent, less than 0.01% formate, sorbate, salicylate and carbonate compounds, and less than about 0.2% of a polymer having a solubility parameter of from about 8.5 to about 12.0 (cal/cm3)½. Further, the composition has a hair friction index of at least 1.07.

Abstract: The present invention relates to topical compositions comprising a vitamin B3 compound which are useful for regulating skin condition, especially for regulating the signs of skin aging.

Abstract: The present invention relates to methods for preventing or treating skin disorders using flavonoid compounds. The present invention also relates to methods for regulating skin condition.

Abstract: The present invention relates to cosmetic compositions, comprising: a.) from about 0.01% to about 50%, by weight, of vitamin B3 compound; b.) from about 0% to about 90%, by weight, of an emollient component comprising from 0% to about 100%, by weight, of an oil liquid at ambient temperature; c.) from about 0.01% to about 40%, by weight, of a polar solvent; d.) from about 0% to about 90%, by weight, of a solidifying agent; and e.) from about 0% to about 90%, on an anhydrous basis, of a color wherein the vitamin B3 compound is added to the composition such that the concentration of the vitamin B3 compound exceeds the saturation solubility of the vitamin B3 compound in the polar solvent.

Abstract: The present invention relates to topical compositions comprising a vitamin B3 compound which are useful for regulating skin condition, especially for regulating the signs of skin aging.

Abstract: The present invention relates to a substantially dry, disposable personal care article suitable for cleansing, said article comprising: a) a water insoluble substrate comprising a creped nonwoven layer wherein said layer has a Crepe Ratio of from about 4.5 to about 45; and b) a cleansing component disposed adjacent to said creped nonwoven layer, wherein said component comprises from about 10% to about 1000%, by weight of the water insoluble substrate, of a lathering surfactant. The present invention further relates to a substantially dry, disposable personal care article suitable for conditioning wherein the above-described article comprises a therapeutic benefit component, disposed adjacent to said water insoluble substrate, wherein said component comprises from about 10% to about 1000%, by weight of the water insoluble substrate, of a therapeutic benefit component in addition to or in lieu of the cleansing component.