Abstract: The present invention relates to the use, in a cosmetic composition, of an extract of at least one part of an orchid of the species Vanda coerulea, as an agent for maintaining or restoring the hydration state of the skin, said composition also containing a cosmetically acceptable excipient. This skin hydrating effect is obtained in particular by stimulating the expression of aquaporin 3 and of the LEKTI protein. The invention also relates to a cosmetic skincare method for the purpose of improving the hydration state of said skin.
Abstract: The invention relates to the therapeutic use of oligonucleotides or oligonucleotide analogs as immunostimulatory agents in immunotherapy applications. The invention provides methods for enhancing the immune response caused by immunostimulatory oligonucleotide compounds.
Type:
Grant
Filed:
October 27, 2003
Date of Patent:
October 4, 2011
Assignee:
Idera Pharmaceuticals, Inc.
Inventors:
Ekambar R. Kandimalla, Qiuyan Zhao, Dong Yu, Sudhir Agrawal