Patents Represented by Attorney G. Kenneth Aventis Pasteur, Inc. Smith

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  • Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
    Patent number: 6146902
    Abstract: Disclosed and claimed are a method for the purification of polysaccharide-protein conjugate vaccines by ultrafiltration in a saturated solution of ammonium sulfate. The ultrafiltration method of the present invention provides an efficient, readily scalable method for removal of unbound polysaccharides from polysaccharide-protein vaccines, thereby improving the purity and consistency of the polysaccharide-protein vaccines.
    Type: Grant
    Filed: December 29, 1998
    Date of Patent: November 14, 2000
    Assignee: Aventis Pasteur, Inc.
    Inventor: Ronald McMaster