Abstract: The invention relates to compounds of general formula (I):
in which R, R1, R2, X and Y are as defined in the description, their geometrical and/or optical isomers, and their addition salts with a pharmaceutically-acceptable acid or base, as well as to medicaments containing the same.
Type:
Grant
Filed:
June 4, 1999
Date of Patent:
May 15, 2001
Assignee:
Adir et Compagnie
Inventors:
Christian Marazano, Delphine Compere, Bhupesh Chandra Das, Jean Lepagnol
Abstract: The present invention relates to a process for the preparation of high-grade chloramine by the action of commercial eau de Javelle of 100 chlorometric degrees on a solution of ammonia in the presence of ammonium chloride. According to this process, the chloramine is obtained having a content greater than or equal to 2 mol L−1, that is to say, greater than or equal to 10.3%. The process can be carried out continuously or discontinuously.