Patents Represented by Attorney, Agent or Law Firm Gabor L. Szekeres
  • Patent number: 7806920
    Abstract: A multi-leaflet valve adapted to serve as a prosthesis for diseased native valve of a mammal is incorporated in self-expandable or inflatable endovascular stents or stents to form a combination which is introduced on a catheter with a guide wire into the circulatory system of the mammal to replace the diseased native valve. Once the combination is at the desired location the stent is caused to expand and affix itself to the patient's vessel wall. The prosthetic valve has the shape of a truncated cone that has an inflow and an outflow orifice with leaflets forming the outflow orifice and forming a plurality of commissures. A first flexible circular support is affixed in a substantially circular fashion around the truncated cone in proximity of the inflow orifice, and a second flexible circular support is affixed at the location of the commissures to form a circle around the truncated cone in proximity of the outflow orifice.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: October 5, 2010
    Assignee: The International Heart Institute Of Montana Foundation
    Inventor: Carlos Duran
  • Patent number: 7807720
    Abstract: Compounds having the formula wherein the symbols have the meaning described in the specification are hydroxamic acid derivatives of 3-phenyl-propionic acid and capable of inhibiting the lethal effects of infection by anthrax bacteria and are useful in the treatment of poisoning by anthrax.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: October 5, 2010
    Assignee: PanThera Biopharma, LLC
    Inventors: Alan T. Johnson, Guan-Sheng Jiao
  • Patent number: 7802566
    Abstract: A barbecue kit includes a threaded rod having a bore in its interior along its longitudinal axis. An elongated stake having a sharp and a blunt end loosely fits into the interior bore of the threaded rod. The combination of rod and stake include a functional mechanism for allowing the threaded rod to act as a slide hammer to drive the stake into the ground without allowing the rod to fall along the entire length of the stake. A grill having a handle includes a plate with a substantially circular cut-out. The distance and configuration of the cut-out and handle are dimensioned in such a way that the grill can be hung at any place on the threaded rod with the circular cut-out engaging the threads. A pan suitable for holding items to be cooked, or charcoal, or like fuel suitable for cooking, has a like handle which is nevertheless removable and reversibly mountable on the pan. The pan can be similarly hung on the rod either with its hollow or with its substantially flat side up on the threaded rod.
    Type: Grant
    Filed: March 27, 2006
    Date of Patent: September 28, 2010
    Inventor: Robert Faught
  • Patent number: 7762535
    Abstract: A stave press assembly for holding a wooden stave or other work piece while the stave is fabricated into a bow or other operations are performed on the work piece, has an immovable pressure plate disposed nominally horizontally when the press is attached to a support surface, and a movable pressure plate which can grip an irregularly shaped wooden stave or other work piece by moving it in a downwardly direction toward the immovable pressure plate. The movable pressure plate is pivotable to a limited extent in order to provide a gripping surface for irregularly shaped items and each pressure plate is lined with resilient high friction material.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: July 27, 2010
    Assignee: Warwick Ideas, LLC
    Inventor: Jon Warwick
  • Patent number: 7407795
    Abstract: Two different strains of Cordyceps sinensis are placed at two different locations in a medium containing purified rattle snake venom and the two strains are allowed to grow until they meet in a boundary zone where a hybrid strain is formed due to exchange of genetic material. The hybrid strain is allowed to grow and is harvested and can be analyzed for the presence and quantity of desired medicinal substances. The amount of N6-(2-hydroxyethyl)-adenosine in a Cordyceps sinensis strain or product sample is a reliable indicator of the overall health benefiting qualities of the strain or sample. Strains of Cordyceps sinensis, are grown in a substrate at 20 to 22° C. at sea level atmospheric pressure for 28 to 30 days in diffuse light, and thereafter in an atmosphere containing approximately 50% of oxygen of the sea level atmosphere, at approximately 3° C.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: August 5, 2008
    Inventors: Phillip D. Cleaver, John C. Holliday, Megan Loomis Powers
  • Patent number: 7351737
    Abstract: Compounds of the formula where the variables are defined in the specification have cytochrome P450RAI-1 and P450RAI-2 inhibitory activity, and are suitable for treatment of mammals with conditions which are treatable with retinoids, or which are controlled by or responsive to the organism's native retinoic acid. Formulations containing the compounds of the invention can also be co-administered with retinoids and/or Vitamin A to enhance or prolong the effects of medications containing retinoids, Vitamin A, or of the organism's native retinoic acid.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: April 1, 2008
    Assignee: Allergan, Inc.
    Inventors: Jayasree Vasudevan, Liming Wang, Xiaoxia Liu, Kwok-Yin Tsang, Yang-Dar Yuan, Roshantha A. Chandraratna
  • Patent number: 7345077
    Abstract: Compounds of Formula 1 where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and/or sedatory activity. These compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula 1 where X is O also have the advantageous property that they have no or only minimal cardivascular and/or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and/or sedatory activity.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: March 18, 2008
    Assignee: Allergan, Inc.
    Inventors: Ken Chow, Todd Heidelbaugh, Daniel Gil, Michael Garst, Larry A. Wheeler, Phong X. Nguyen, Dario G. Gomez
  • Patent number: 7294716
    Abstract: Synthetic methods for preparing isomerically pure N-arylsulfonyl derivatives of proton pump inhibitors which include a substituted benzimidazole nucleus are shown by the synthetic schemes and experimental description.
    Type: Grant
    Filed: July 13, 2004
    Date of Patent: November 13, 2007
    Assignee: Allergan, Inc.
    Inventors: Michael E. Garst, Lloyd Jay Dolby, Shervin Esfandiari, Vivian Rose MacKenzie, Alfred Arthur Avey, Jr., David Charles Muchmore, Geoffrey Kenneth Cooper, Thomas C. Malone
  • Patent number: 7276522
    Abstract: The compound of the formula wherein the * indicates an asymmetric carbon, is specific to alpha2B adrenergic receptors in preference over alpha2A and alpha2C adrenergic receptors, and as such has no or only minimal cardivascular and/or sedatory activity. The compound is useful as medicament in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors.
    Type: Grant
    Filed: September 24, 2004
    Date of Patent: October 2, 2007
    Assignee: Allergan, Inc.
    Inventors: Todd M. Heidelbaugh, Ken Chow, Phong Nguyen, Daniel Gil, John E. Donello
  • Patent number: 7226626
    Abstract: Novel food, dietary supplement and nutraceutical products containing phenol/protein complexes derived from vegetable sources have high antioxidant activity and very high levels of protein. The products provide novel means for administering high levels of plant antioxidants to human and mammals in the form of a protein concentrate. Due to their high antioxidant capacity these novel products are useful as aids in the prevention and treatment of many diseases.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: June 5, 2007
    Assignee: Cyvex, Technologies, Inc.
    Inventors: Michael T. Yatcilla, Gilbert Gluck
  • Patent number: 7160972
    Abstract: A thermally stable polysiloxane composition is a cross-linked product of a Part A composition, of a Part B composition and a catalyst, the Part A composition being a polysiloxane having 60 to 75 percent by weight phenyl groups, the Part B composition being a polysiloxane having 50 to 80 percent by weight phenyl groups. The composition has the properties of optical clarity as measured by 90% or greater transmission of light of 400 nm wavelength in a 1.0 centimeter path, a refractive index at 589 nm of 1.545 or greater and still has 90% or greater transmission of light of 400 nm wavelength in a 1.0 centimeter path after exposure to 150° C. for 6 hours. The composition is well suited for application as an optically transmissive cover or lens for light emitting diodes and for use in other optical and related devices.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: January 9, 2007
    Assignee: NuSil Technology LLC
    Inventors: Nickelous David Young, David B. Stone, legal representative, Robert Vincent Thomaier, Keith Bryan Reichel, David Stevenson Stone, deceased
  • Patent number: 7160320
    Abstract: A multi-leaflet valve adapted to serve as a prosthesis for diseased native valve of a mammal is constructed of biologic membrane or of biocompatible synthetic membrane. The valve has the shape of a truncated cone that has an inflow and an outflow orifice with leaflets forming the outflow orifice and forming a plurality of commissures. A first flexible stent is removably affixed in a substantially circular fashion around the truncated cone in proximity of the inflow orifice, and a second flexible stent is removably affixed at the location of the commissures to form a circle around the truncated cone in proximity of the outflow orifice. The stents maintain the shape of the valve during the surgical implantation procedure. Each stent independently can be left in the valve or can be removed during the implantation procedure based upon the judgement of the cardiac surgeon performing the implantation procedure.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: January 9, 2007
    Assignee: The International Heart Institute of Montana Foundation
    Inventor: Carlos Duran
  • Patent number: 7125418
    Abstract: A multi-leaflet valve adapted to serve as a prosthesis for diseased native valve of a mammal is incorporated in self-expandable or inflatable endovascular stents or stents to form a combination which is introduced on a catheter with a guide wire into the circulatory system of the mammal to replace the diseased native valve. Once the combination is at the desired location the stent is caused to expand and affix itself to the patient's vessel wall. The prosthetic valve has the shape of a truncated cone that has an inflow and an outflow orifice with leaflets forming the outflow orifice and forming a plurality of commissures. A first flexible circular support is affixed in a substantially circular fashion around the truncated cone in proximity of the inflow orifice, and a second flexible circular support is affixed at the location of the commissures to form a circle around the truncated cone in proximity of the outflow orifice.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: October 24, 2006
    Assignee: The International Heart Institute of Montana Foundation
    Inventors: Carlos Duran, Mark Sanz
  • Patent number: 7091232
    Abstract: Compounds of Formula 1 where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and/or sedatory activity. These compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula 1 where X is O also have the advantageous property that they have no or only minimal cardivascular and/or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and/or sedatory activity.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: August 15, 2006
    Assignee: Allergan, Inc.
    Inventors: Ken Chow, Todd Heidelbaugh, Daniel Gil, Michael Garst, Larry A. Wheeler, Phong X. Nguyen, Dario G. Gomez
  • Patent number: 7026487
    Abstract: Compounds of the formula where the symbols are as defined in the specification, have retinoid agonist, antagonist or negative hormone-like biological activity.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: April 11, 2006
    Assignee: Allergan, Inc.
    Inventors: Richard L. Beard, Thong Vu, Diana F. Colon, Vidyasagar Vuligonda, Roshantha A. Chandraratna
  • Patent number: 7019034
    Abstract: Diabetic mammals are treated with compounds that are significantly more efficacious as agonists of RXR? retinoid receptors than as agonists of RXR? or RXR? retinoid receptors. The treatment reduces serum glucose and triglyceride levels of the mammals without the undesirable side effects of reducing serum thyroxine levels and a transient increase in serum triglyceride levels Compounds suitable for use in the methods of treatments of the present invention are selected by testing and identifying compounds of selective or specific efficacy as agonists of RXR? retinoid receptors in preference over RXR? and/or RXR? retinoid receptors. Novel compounds used in the methods of the invention have Formula 1 where the variables are defined as disclosed in the specification.
    Type: Grant
    Filed: December 17, 2003
    Date of Patent: March 28, 2006
    Assignee: Allergan, Inc.
    Inventors: Yang-Dar Yuan, Richard L. Beard, Roshantha A. Chandraratna
  • Patent number: 7004101
    Abstract: The hull of a boat includes an opening which is closed by a door attached to the hull with a hinge and capable of limited pivoting motion on the hinge with a substantially horizontal axis of the pivot. In its upright first extreme position the door comprises a part of the hull. In a second folded down extreme position the door is substantially parallel with the water surface and can act as a loading platform and also as a stabilizer against wave action in rough waters.
    Type: Grant
    Filed: November 29, 2004
    Date of Patent: February 28, 2006
    Assignee: The Mardikian Family Trust
    Inventor: Albert Mardikian
  • Patent number: 6936636
    Abstract: Compounds of the formula: where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects of reducing serum thyroxine levels and transiently increasing triglyceride levels.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: August 30, 2005
    Assignee: Allergan, Inc.
    Inventors: Santosh Sinha, Kwok Yin Tsang, Smita Bhat, Roshantha A. Chandraratna
  • Patent number: 6923509
    Abstract: A remotely activated electro mechanical device is mounted in the dual chamber brake system of a vehicle or trailer. The device includes a solenoid valve and a receiver decoder which controls the valve in response to a coded signal ideally available only to law enforcement to vent pressure in the emergency chamber of a dual chamber brake system to automatically apply the brakes thereby bringing a moving vehicle to a stop. The device is also responsive to a second, different coded signal, available only to authorized users to vent pressure in the emergency chamber and to lock the brakes by preventing pressurized air from being supplied to the dual chamber brake system of a stopped or parked vehicle. The device is also responsive to coded signals which reverse the above-noted actions.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: August 2, 2005
    Assignee: Cargo Safe, Inc.
    Inventor: Burton Barnett
  • Patent number: 6904863
    Abstract: A self-retracting step assembly is attached to a swimming platform provided on the rear of the hull of a boat. The self-retracting step assembly includes a ladder comprising a series of telescoping tubes which enable its extension and retraction. The step assembly including the ladder assembly are attached to the swimming platform in a position in which the ladder is capable of extending into the water wherein the watercraft or boat floats. The telescoping ladder assembly can be extended and placed from a normally horizontal position into an inclined position wherein at least the last step of the ladder reaches the water. The energy for extending the ladder is supplied by a human user. The step assembly includes a motor or mechanical means for storing the energy used for extending the ladder. The ladder assembly is locked into the extended and inclined position by an improved mechanism that is located within the assembly attached to the swimming platform.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: June 14, 2005
    Assignee: The Mardikian Family Trust
    Inventors: Albert Mardikian, Raffi Pinedjian, Aaron Delaby