Patents Represented by Attorney, Agent or Law Firm Gabriel L. Kleinman
  • Terpenoid lactone compounds and their production process
    Patent number: 6221899
    Abstract: This invention provides terpenoid lactone compounds, and processes for producing the terpenoid lactone compounds, which comprise cultivating Oidiodedron griseum FERM BP-5778 and then isolating the terpenoid lactone compounds from the fermentation broth. The present invention also provides a pharmaceutical composition comprising the teipenoid lactone compound, which is useful in the treatment of IL-1 and TNF mediated diseases or the like.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: April 24, 2001
    Assignee: Pfizer Inc.
    Inventors: Hiroyuki Nishida, Masaya Ikunaka, Nobuji Yoshikawa, Katsuomi Ichikawa, Nakao Kojima