Abstract: A portable, integrated physiological monitoring system is described for use in clinical outpatient environments. This systems consists of a plethora of sensors and auxiliary devices, an electronics unit (100) that interfaces to the sensors and devices, and a portable personal computer (102). Electrodes (106) are provided to acquisition electrocardiographic, electroencephalographic, and neuromuscular signals. Electrodes (108) are provided to stimulate neural and muscular tissue. A finger pulse oximeter (110), an M-mode ultrasonic transducer (112), an airflow sensor (114), a temperature probe (120), a patient event switch (116), and an electronic stethoscope (118) are provided. A portable personal computer (102) interfaces to the electronics unit (100) via a standard parallel printer port interface (258) to allow communication of commands and information to/from the electronics unit (100).