Abstract: Recombinant yeast are provided having, in one aspect, multiple exogenous LDH genes integrated into the genome, while leaving native PDC genes intact. In a second aspect, recombinant yeast are provided having an exogenous LDH gene integrated into its genome at the locus of a native PDC gene, with deletion of the native PDC gene. The recombinant yeast are useful in fermentation process for producing lactic acid.
Type:
Grant
Filed:
May 30, 2003
Date of Patent:
May 19, 2009
Assignee:
Cargill, Inc.
Inventors:
Ben Hause, Vineet Rajgarhia, Pirkko Suominen