Abstract: The invention provides compositions and methods for measuring human serum hepcidin levels. The invention provides methods for the oxidative refolding of a hepcidin polypeptide to a form that is mature, bioactive and folded as in the native configuration and molecular mass; a method for measuring the level of native, bioactive hepcidin in a vertebrate animal.
Type:
Grant
Filed:
November 11, 2008
Date of Patent:
June 29, 2010
Assignee:
Intrinsic Lifesciences
Inventors:
Xavier Lauth, Mark E. Westerman, Vaughn E. Ostland, Jason A. Stannard, Michael W. Pennington