Abstract: This invention is directed to quinoline/quinoxaline compounds which inhibit platelet-derived growth factor or p56lck tyrosine kinase activity, to pharmaceutical compositions comprising these compounds, and to the use of these compounds for treating a patient suffering from or subject to disorders/conditions involving cellular differentiation, proliferation, extracellular matrix production or mediator release and/or T cell activation and proliferation.
Type:
Grant
Filed:
September 29, 2000
Date of Patent:
March 4, 2003
Assignee:
Aventis Pharmaceuticals Inc.
Inventors:
Michael R. Myers, Wei He, Alfred P. Spada, Martin P. Maguire