Abstract: A system and method for implanting a wrap on a patient's heart or other organ provides a wrap having finger-engagement members typically defining loops that encompass all or a substantial portion of the fingers of a surgeon's treatment hand. The loops retain the fingers to the wrap during implant, and enable the fingers to be detached after the procedure is complete. The loops can be detachable from the wrap after the procedure is completed or can be formed to remain with the wrap.

Abstract: The invention relates to sensors for detecting a time-varying current by employing a plurality of coils with separate windings, disposed on separate toroidal cores, that are placed in close proximity of each other so that each coil responds independently to the same current. The current produces a time-varying magnetic field which in turn induces a plurality of voltages across the coils that can be combined to provide a resultant signal. Some embodiments of the invention employ coils with opposite windings to obtain signals with opposite phases and combine these signals through differential detection means to obtain a combined signal. One aspect of the invention relates to production of a wide-band or a selectable band-width sensor by preparing at least one coil to be dissimilar with respect to the others. In addition, the invention provides provisions for easy calibration of the sensor.

Abstract: A non-blood contacting, implantable heart assist system surrounds the natural heart and provides resistance to cardiac hypertrophy. The restraint system is composed of adjacent tube pairs arranged along a bias with respect to the axis of the heart and bound in a non-distensible sheath forming a heart wrap. The tube pairs are tapered at both ends such that when they are compressed they approximately follow the surface of the myocardium. Inflation of the tube pairs with a compressible fluid causes the wrap to exert a restraining force on the heart to prevent overexpansion during diastole.

Abstract: A unified, non-blood contacting, implantable heart assist system surrounds the natural heart and provides circumferential contraction in synchrony with the heart's natural contractions. The pumping unit is composed of adjacent tube pairs arranged along a bias with respect to the axis of the heart and bound in a non-distensible sheath forming a heart wrap. The tube pairs are tapered at both ends such that when they are juxtaposed and deflated they approximately follow the surface of the diastolic myocardium. Inflation of the tube pairs causes the wrap to follow the motion of the myocardial surface during systole. A muscle-driven or electromagnetically powered energy converter inflates the tubes using hydraulic fluid pressure. An implanted electronic controller detects electrical activity in the natural heart, synchronizes pumping activity with this signal, and measures and diagnoses system as well as physiological operating parameters for automated operation.

Abstract: Drug delivery vehicles and catheter systems are disclosed for controlled release of therapeutic agents employing a permeable hydrogel membranes a reservoir for an inflation fluid carrying a therapeutic agent. The membrane devices of the present invention can be used in conjunction with a catheter or similar instrument having an elongated hollow body member and a lumen extending therethrough to permit fluid communication between a proximal infusion port and a permeable membrane disposed at the distal end of the catheter body. The membrane preferably comprises an expandable, hydrophilic polymer having a predetermined permeability with respect to an inflation fluid. One preferred hydrophilic polymer is a hydrogel capable of imbibing an aqueous solution to reach a state in which it comprises between 50% and 98% water by weight in equilibrium. In this state, the hydrogel membrane serves to control the rate of medicament delivery.