Abstract: The present invention relates to a compound of formula I wherein R, X and n are defined hereinabove, and to a pharmaceutically acceptable salt thereof. The compound may be used for the treatment of diseases related to the A2A receptor.
Type:
Grant
Filed:
May 18, 2004
Date of Patent:
December 4, 2007
Assignee:
Hoffmann-La Roche Inc.
Inventors:
Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
Abstract: Vectors and recombinant bacteria for overproducing riboflavin, in which nucleic acid overproducing riboflavin biosynthetic proteins is introduced in the chromosome of the host organism, e.g. at multiple sites and in multiple copies per site. A rib operon having at least five genes is used to make such recombinant bacteria.
Type:
Grant
Filed:
August 24, 1998
Date of Patent:
July 20, 1999
Assignee:
Roche Vitamins Inc.
Inventors:
John B. Perkins, Alan Sloma, Janice G. Pero, Randolph T. Hatch, Theron Hermann, Thomas Erdenberger