Abstract: Recombinant DNA sequences encoding the DNA polymerase activity of Thermus thermophilus can be used to construct recombinant vectors and transformed host cells for production of the activity. T. thermophilus DNA polymerase is an .about.94 kDa protein especially useful in the DNA amplification procedure known as the polymerase chain reaction.
Type:
Grant
Filed:
February 6, 1995
Date of Patent:
April 8, 1997
Assignee:
Hoffmann-La Roche Inc.
Inventors:
David H. Gelfand, Frances C. Lawyer, Susanne Stoffel