Abstract: An portable tracking device integrating a mobile phone module (e.g. based on GSM or 3G networks), a GPS module, a radio Beacon and ultrasonic beacon. The tracking device is normally in a hibernated state when the entire device consumes little energy and require no periodically changing or recharging batteries to power the device. It consumes power from the primary battery only when a tracking process is actually taken place. With this portable tracking device on the person who is unable to affirmatively report his or her whereabout, the remote center and/or a search team can communicate the GPS module, radio beacon and ultrasonic beacon of the tracking device via the mobile phone module based on existing wireless communication technologies, such SMS, GPRS, ect, on GSM or 3 G networks, which also serves as a means of initial rough estimation of the tracking device's location.

Abstract: The present invention relates to a process for the preparation of the enantiomeric forms of 2-substituted 2-(2,5-dioxoimidazolidin-1-yl)acetic acid derivatives of the formula I, wherein R1, R2 and R3 have the meanings given in the claims, by stereodifferentiating conversion of mixtures of the enantiomers with the aid of enzymes.

Abstract: This invention is directed to a pharmaceutical composition comprising the sodium-hydrogen exchanger (NHE) inhibitor cariporide and an angiotensin converting enzyme (ACE) inhibitor which exhibits unexpectedly efficacious properties for preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life, and to methods of preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life comprising administering pharmaceutically effective amounts of the sodium-hydrogen exchange inhibitor cariporide and an ACE inhibitor.

Abstract: Ortho, ortho-substituted nitrogen-containing bisaryl compounds, processes for their preparation, their use as medicaments, and pharmaceutical preparations including their use as antiarrhythmic active compounds, for example, for the treatment and prophylaxis of atrial arrhythmias, e.g. atrial fibrillation (AF) or atrial flutters.