Patents Represented by Attorney Gerald Rosen
  • Patent number: 5391706
    Abstract: A method of purifying granulocyte-macrophage colony-stimulating factor (GM-CSF), particularly recombinant human GM-CSF, in good yield and with retention of biological activity, comprising sequential anion-exchange, dye-ligand affinity, gel filtration and reversed-phase chromatography is disclosed.
    Type: Grant
    Filed: September 21, 1993
    Date of Patent: February 21, 1995
    Assignee: Schering Plough Corporation
    Inventors: Paul P. Trotta, Gail F. Seelig, Robert A. Kosecki, Paul Reichert