Patents Represented by Attorney Gerard P. Norton

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  • Senscent cell-derived inhibitors of DNA synthesis
    Patent number: 6372249
    Abstract: The use of liposomal formulations, particularly formulations of positively charged and neutral lipids facilitates cellular uptake of SDI molecules. The transcription and/or expression of SDI-1-encoding nucleic acid molecules is facilitated by constructs that contain intervening untranslated regions.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: April 16, 2002
    Assignee: Baylor College of Medicine
    Inventors: James R. Smith, David J. Drutz, Deborah R. Wilson, Louis A. Zumstein
  • Mimetics of senescent cell derived inhibitors of DNA synthesis
    Patent number: 5596079
    Abstract: Phage display methods were used to identify mimetics of SDI-1. Such mimetics are small peptides that are capable of binding to cyclin molecules, especially CDK2. The invention is directed to the mimetics and to methods for producing them.
    Type: Grant
    Filed: May 24, 1994
    Date of Patent: January 21, 1997
    Inventors: James R. Smith, Brian K. Kay