Abstract: The present invention relates to methods for making racemic 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone and (+)-2-(7-chloro-1,8-naphthyridine-2-yl)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinone.
Type:
Grant
Filed:
March 27, 2003
Date of Patent:
September 27, 2005
Assignee:
Indevus Pharmaceuticals, Inc.
Inventors:
Sandra Marie Jennings, Timothy Lee Stuk
Abstract: A novel process for sterilizing an article made from polymeric material by radiation sterilization. The article is enclosed in a gas impermeable package together with an oxygen absorber for a time sufficient to consume substantially all the oxygen in the package and the oxygen dissolved in the polymeric material. The article is prefereably intended for medical use and can contain a radiation sterilizable parenterally administerable preparation.
Type:
Grant
Filed:
February 21, 1997
Date of Patent:
March 16, 1999
Assignee:
Pharmacia & Upjohn AB
Inventors:
Anna Ahlqvist, Kjell Berglund, Stefan Lundmark, Jimmie Ward