Patents Represented by Attorney, Agent or Law Firm Gilbert V. Voy
  • Pharmaceutical formulation
    Patent number: 6245352
    Abstract: The present invention relates to a pharmaceutical formulation, which comprises from 5 to 15% by weight of tamoxifen citrate and a first disintegrant which is croscarmellose sodium, the percentage by weight of croscarmellose sodium present in the formulation being chosen such that, in six 20 mg unit doses, an average of at least 65 percent by weight of the tamoxifen citrate in the formulation will dissolve within 10 minutes in 1000 mL of 0.02N hydrochloric acid at 37° C. when stirred at 100 rpm.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: June 12, 2001
    Assignee: Eli Lilly and Company
    Inventors: Gordon Nelson Arbuthnot, Karen Klapper Lomas, Glenn Alan Meyer