Abstract: This invention relates to monoamine oxidase-B (MAO-B) inhibitory 5-substituted 2,4-thiazolidinediones, such as Formula I, to pharmaceutical compositions thereof, process of preparation, and methods of use in mammals to treat cognitive disorders, neurological dysfunction, and/or mood disturbances such as, but not limited to degenerative nervous system diseases.
Type:
Grant
Filed:
July 17, 1992
Date of Patent:
July 5, 1994
Assignee:
The Du Pont Merck Pharmaceutical Company