Abstract: Genotypes and haplotypes for thirteen polymorphic sites in the &bgr;2-adrenergic receptor (&bgr;2AR) gene are disclosed. Compositions and methods for predicting genetic predisposition to disease associated with polymorphic sites in the (&bgr;2AR) gene, as well as for predicting response to &bgr;-agonists, are also disclosed.
Type:
Grant
Filed:
March 16, 2001
Date of Patent:
July 1, 2003
Assignee:
Genaissance Pharmaceuticals, Inc.
Inventors:
Connie M. Drysdale, Richard S. Judson, Stephen B. Liggett, Krishnan Nandabalan, Catherine B. Stack, J. Claiborne Stephens