Patents Represented by Attorney GlaxoSmithKline Corporate Intellectual Property

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  • Vaccine
    Patent number: 7655235
    Abstract: The invention relates to polynucleotides for DNA vaccination which polynucleotides encode an HIV envelope protein or fragment or immunogenic derivative, which is non-glycosylated when expressed in a mammalian target cell, operably linked to a heterologous promoter. Preferably the HIV envelope molecule, such as gp120 or gp140 or gp160, lacks a functional secretion signal. It may be fused to additional HIV proteins such as Nef, Gag, RT or Tat.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: February 2, 2010
    Assignee: Glaxo Group Limited
    Inventor: Peter Franz Ertl
  • Immunization with an attenuated human rotavirus
    Patent number: 7579008
    Abstract: The invention provides a method of inducing an immune response against rotavirus infection from one rotavirus serotype, the method comprising administering to a subject a composition comprising an attenuated rotavirus vaccine from a different serotype. There is in particular provided a method of inducing an immune response against rotavirus infection from a non-G1 serotype, the method comprising administering to a subject a composition comprising an attenuated rotavirus vaccine from a G1 serotype.
    Type: Grant
    Filed: August 30, 2004
    Date of Patent: August 25, 2009
    Assignee: GlaxoSmithKline Biologicals, s.a.
    Inventors: Brigitte Desiree Alberte Colau, Beatrice Arsene Virginie De Vos