Abstract: Scytophycins A, B, C, D and E, an aldehyde and alcohol derivative of scytophycin B and the specified alkanoyl and benzoyl esters of scytophycins A, B, C, D and E and the B derivatives (scytophycin compounds) are novel antineoplastic and antifungal agents. Antifungal compositions containing a scytophycin compound and methods of inhibiting fungi, especially plant pathogenic fungi, using these compositions are included. A method for producing the scytophycin complex, comprising scytophycins A, B, C, D and E, using a new strain of the blue-green alga Scytonema pseudohofmanni, and a biologically purified culture of the alga are also provided.
Type:
Grant
Filed:
November 19, 1990
Date of Patent:
January 25, 1994
Assignee:
University of Hawaii
Inventors:
Richard E. Moore, Eiichi Furusawa, Ted R. Norton, Gregory M. L. Patterson, Jon S. Mynderse
Abstract: A novel product obtained by reacting an alkali metal salt of nicotinic acid with a trivalent chromium salt and having glucose tolerance factor activity, a process for its production and a method for its use, are disclosed.
Abstract: Disclosed is a gasket, system and method for forming and sealing an electrophoresis gel casting chamber by utilizing a sealing gasket having a plate retention channel and an integral sealing gasket portion. The gel casting chamber system includes electrophoresis gel plates and spacers which are particularly adapted for use with the disclosed gasket.