Abstract: Methods for producing hybrids between domestic and wild soybean that are fertile and can be further bred with other soybean plants are provided, thus allowing transfer of desirable traits and genes from the wild soybean into the domestic soybean. This invention also provides novel media for producing callus and multiple somatic embryos, as well as novel media for producing multiple shoots from the embryos. The hybrid plants are made fertile by colchicine treatment to double their chromosome number so that they can be backcrossed into domestic soybean. These methods and media allow the production of elite soybean lines containing traits or genes from wild soybean as well as a minimum amount of additional wild soybean DNA. Backcrosses containing only one wild soybean chromosome can be produced, as well as sets of such backcrossed lines that each contain one chromosome from the wild ancestor, but collectively all the wild chromosomes from the hybrid ancestor.

Abstract: An axle assembly for a vehicle, the axle assembly comprising a differential gear having an input for connection to a drive shaft, and a first wheel hub to support a first wheel and a second wheel hub to support a second wheel, the first wheel hub and the second wheel hub being drivingly connected to the differential gear, wherein the first wheel hub is drivingly connected to the differential gear via a reverser mechanism, the reverser mechanism having a first operating mode where the first wheel hub is driven in the same direction as the second wheel hub and a second operating mode where the first wheel hub is driven in the opposite direction to the second wheel hub.

Abstract: The invention provides improved therapeutic and diagnostic fullerenes and endohedral fullerenes. The fullerenes and endohedral fullerenes of the invention are derivatized with at least two charged functional groups (and preferably more than two charged functional groups) to provide for water-solubility and improved in vivo biodistribution. Improved derivatized fullerenes and endohedral fullerenes carry a plurality of functional groups at least two of which are charged. Preferably at least about ? of the possible derivations sites on the fullerene caged carry derivatives and preferably at least about ½ of the functional groups on the fullerene cage are charged groups. The invention also provides water-soluble endohedral metallofullerene with improved biodistribution which are useful as in vivo imaging agents, including MRI contrast agents.

Abstract: Methods of making alkyl esters are described herein. The methods are capable of using raw, unprocessed, low-cost feedstocks and waste grease. Generally, the method involves converting a glyceride source to a fatty acid composition and esterifying the fatty acid composition to make alkyl esters. In an embodiment, a method of making alkyl esters comprises providing a glyceride source. The method further comprises converting the glyceride source to a fatty acid composition comprising free fatty acids and less than about 1% glyceride by mass. Moreover, the method comprises esterifying the fatty acid composition in the presence of a solid acid catalyst at a temperature ranging firm about 70° C. to about 120° C. to produce alkyl esters, such that at least 85% of the free fatty acids are converted to alkyl esters. The method also incorporates the use of packed bed reactors for glyceride conversion and/or fatty acid esterification to make alkyl esters.

Abstract: The present invention relates to the field of a medicine for treating diseases associated with inflammation, immunity or infection, and in particular, to glycyrrhetinic acid-30-amide derivatives of general formula I and their preparation, and a pharmaceutical composition containing the same. Said derivatives and composition exhibit anti-inflammatory, analgesic, anti-allergic, cough-preventing, liver-protecting and anti-viral properties, wherein each group is as defined in the description.

Abstract: The invention provides a method for contacting liquid with an ion exchange resin comprising introducing liquid into a process tank containing ion exchange resin at an inlet (2) and removing liquid that has been contacted with resin from the process tank at an outlet, the outlet being located above the inlet (2), the process tank including a resin containment region (7, 9) disposed between the inlet (2) and the outlet to impede the upward flow of the resin as it becomes entrained in the liquid flowing from the inlet to the outlet, and a contactor region for promoting contact between the resin and the liquid located below the containment region (7, 9), said containment region (7, 9) containing an array of settling members through which the liquid and resin upflow and which impede the flow of the resin to a sufficient extent that it is substantially contained within or below the containment region (7, 9). Apparatus for performing this method is also provided.

Abstract: Lantibiotics are synthesized on ribosomes as prepeptides and post-translationally modified to a mature form. These modifications include dehydrations and cyclizations. Compounds and related methods of generating compounds, modified by dehydration, cyclization, or dehydration and cyclization, are disclosed. The disclosure includes in vitro approaches to effecting dehydration and cyclization leading to production of biologically active compounds such as lantibiotics and variants thereof. Synthetic variants and methods including combinatorial approaches for generating diverse lantibiotics and other compounds are disclosed. The invention has broad potential for applications including food, agricultural, and medical industries.

Abstract: The invention provides devices and methods for collecting vapor gas generated by an oil-containing material within a production tank. The devices and associated methods result in produced oil having a reduced level of dissolved hydrocarbons and recovery of vapor gas for resale. The devices include vapor recovery units connected to conventional oil-production units so that a conventional unit is converted to a low emission unit. In an embodiment, the device is a column separator comprising a perforated, packed spiral baffle with one end that receives vapor gas and a second end for removing gas that has traversed the length of the column separator. Also provided are methods for converting an oil-production unit into a low-emission oil production unit using any of the devices disclosed herein.

Abstract: This invention provides thermal sensors and imagers that are flexible and capable of conforming to curved surfaces and corresponding methods of making and methods of thermal sensing. The thermal sensors contain an array of thermal resistors patterned in a row and column configuration, with each thermal resistor electrically isolated from other thermal resistors within the sensor. Thermal information is obtained from a region by measuring the resistance of each thermal resistor and calculating a thermal resistance for each entry of the array.

Abstract: The object of the present invention is to isolate Rf gene, particularly Rf1 gene derived from radish, and identify its structure. The present invention provides a protein involved in restoration of a cytoplasmic male sterile individual to fertility which has 14 or more pentatricopeptide repeat (hereafter may be abbreviated to PPR) motifs, wherein a group of the motifs is divided into 3 or more blocks, each of the individual blocks has at least 2 or more PPR motifs, and the block in a carboxyl terminal (C terminal) side has 4 PPR motifs.

Abstract: Exogenous cDNA capable of expressing interferon? activity, exogenous interferon? protein, inducers of endogenous interferon? protein activity, inducers of endogenous interferon $ protein activity, inducers of endogenous interferon? activity, or inducers of other immune-enhancing activity can be combined with a vaccine to enhance an immune response. Specifically disclosed are adjuvant and vaccine combinations where the adjuvant comprises a cDNA capable of expressing interferon? activity, a complex comprising polyriboinosinic-polyribocytidilic acid, or a complex comprising polyriboinosinic-polyribocytidilic acid, poly-L-lysine, and carboxymethylcellulose and where the vaccine is a live vaccine virus derived from a virus causing porcine reproductive and respiratory syndrome disease.

Abstract: A method comprising contacting an alcohol, a feed comprising one or more glycerides and equal to or greater than 2 wt % of one or more free fatty acids, and a solid acid catalyst, a nanostructured polymer catalyst, or a sulfated zirconia catalyst in one or more reactors, and recovering from the one or more reactors an effluent comprising equal to or greater than about 75 wt % alkyl ester and equal to or less than about 5 wt % glyceride.

Abstract: A process for the regeneration of loaded ion-exchange resin comprising (a) providing loaded resin for regeneration; (b) providing first stage and third stage regenerant suitable for regenerating loaded resin; (c) providing a plurality of regeneration vessels; (d) filling a regeneration vessel with a desired amount of the loaded resin before filling another regeneration vessel; (e) once a regeneration vessel has been filled, contacting the loaded resin within the vessel with first stage regenerant in a plug flow to provide a first stage regenerated resin; (f) contacting the first stage regenerated resin with third stage regenerant in a plug flow to provide regenerated resin and (g) removing and collecting third stage regenerant from a vessel containing regenerated resin and adding the collected regenerant to the first stage regenerant.

Abstract: The present invention provides structures and devices comprising conductive segments and conductance constricting segments of a nanowire, such as metallic, superconducting or semiconducting nanowire. The present invention provides structures and devices comprising conductive nanowire segments and conductance constricting nanowire segments having accurately selected phases including crystalline and amorphous states, compositions, morphologies and physical dimensions, including selected cross sectional dimensions, shapes and lengths along the length of a nanowire. Further, the present invention provides methods of processing nanowires capable of patterning a nanowire to form a plurality of conductance constricting segments having selected positions along the length of a nanowire, including conductance constricting segments having reduced cross sectional dimensions and conductance constricting segments comprising one or more insulating materials such as metal oxides.

Abstract: A method for inducing melanogenesis in a human subject having a melanocortin 1 receptor (MC1R) variant allele associated with loss of or diminished receptor function comprises administering to said subject an amount of an ?-melanocyte stimulating hormone (?-MSH) analogue effective to induce melanogenesis by the melanocytes in the skin or other epidermal tissue of the subject.

Abstract: Bisphosphonate compounds and related methods of making and using are disclosed, including pyridinium-1-yl, quinolinium-1-yl, and related compounds. The activity of compounds is disclosed in the context of functional assays such as Leishmania major farnesyl diphosphate synthase (FPPS) inhibition, Dictyostelium discoideum growth inhibition, human gamma delta T cell activation, and bone resorption. The applicability of bisphosphonate compounds in the context of parasitic infections, for example against trypanosomes, is disclosed. Further potential applications of the invention are disclosed regarding the treatment of one or more conditions such as bone resorption disorders, cancer, bone pain, infectious diseases, and in immunotherapy.

Abstract: A parimutuel betting game featuring in-game wagers and payoffs, and real time parimutuel style odds, based on events unfolding during a live event, a principal objective being to acquire the largest number of betting tokens by the end of the event. An administrator oversees a plurality of betting lines associated with betting events. Players are allowed to bet tokens on an open betting line until it is closed by the administrator. The line will close at or before the time the situation in the live event changes appreciably, so the posted odds on the betting lines are in synch with the live event. When a line is closed, a new line may open. When a termination event occurs for a given betting event, the betting event is terminated and all lines that opened since the previous termination are paid off simultaneously in parimutuel style. The betting lines preferably have a hierarchical structure. The game may be played over the Internet.

Abstract: A new and distinct tamarillo variety is described. The variety results from selection among a population of seedlings derived from hybridization among red, amber, and yellow-fruited tamarillo selections. This new variety is characterized by bright red skin color and sweet flavor. The new variety appears suitable for the fresh fruit market and has been named ‘Sweeten’.