Patents Represented by Attorney Gregory Houghton
  • Patent number: 8188037
    Abstract: Disclosed are microparticles comprising a somatostatin analogue embedded in a biocompatible pharmacologically acceptable polymer matrix for a long acting release and pharmaceutical compositions comprising such microparticles.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: May 29, 2012
    Assignee: Novartis AG
    Inventors: Markus Ahlheim, Michael Ausborn, Olivier Lambert, Marc Riemenschnitter
  • Patent number: 8163747
    Abstract: The present invention relates to new salt forms of 5-(2,4-dihydroxy-5-isopropyl-phenyl)-4-(4-morpholin-4-ylmethyl-phenyl)-isoxazole-3-carboxylic acid ethylamide, in particular the mesylate, hydrochloride, tartrate, phosphate and hemi fumarate salt thereof; to crystalline forms of such salts; to polymorphs of 5-(2,4-dihydroxy-5-isopropyl-phenyl)-4-(4-morpholin-4-ylmethyl-phenyl)-isoxazole-3-carboxylic acid ethylamide; to hydrates and polymorphs of the new salt forms mentioned above; to the use of the new salt forms mentioned above for the manufacture of a medicament for the treatment of a disorder mediated by Hsp90; to a method for treating a disorder mediated by Hsp90 using the new salt forms; to formulations comprising such salt forms, in particular aqueous solutions suitable for intravenous administration; and to amber glass containers being filled with such formulations.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: April 24, 2012
    Assignees: Novartis AG, Vernalis (R&D) Ltd.
    Inventors: Martin James Drysdale, Brian William Dymock, Christoph Krell, Michael Mutz, Holger Petersen, Weijia Zheng
  • Patent number: 8153672
    Abstract: The invention relates to crystalline forms of 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid and to its amorphous form, to processes for the preparation thereof, to compositions containing the same and their uses for the manufacture of a medicament for the treatment of the human body.
    Type: Grant
    Filed: November 27, 2007
    Date of Patent: April 10, 2012
    Assignee: Novartis AG
    Inventor: Michael Mutz