Patents Represented by Attorney, Agent or Law Firm Gregory Steele
  • Treatment of diseases using endothelin antagonists
    Patent number: 6380241
    Abstract: A compound of the formula (I): or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: April 30, 2002
    Assignee: Abbott Laboratories
    Inventors: Martin Winn, Steven A. Boyd, Charles W. Hutchins, Hwan-Soo Jae, Andrew S. Tasker, Thomas W. von Geldern, Jeffrey A. Kester, Bryan K. Sorensen, Bruce G. Szczepankiewicz, Kenneth J. Henry, Gang Liu, Steven J. Wittenberger, Steven A. King
  • 3-substituted indole angiogenesis inhibitors
    Patent number: 6323228
    Abstract: 3-Substituted indole carbohydrazides having the formula are useful for inhibiting angiogenesis. Also disclosed are angiogenesis-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: November 27, 2001
    Assignee: Abbott Laboratories
    Inventors: Nwe Y. BaMaung, Richard A. Craig, Megumi Kawai, Jieyi Wang
  • Self-emulsifying systems containing anticancer medicament
    Patent number: 6316497
    Abstract: The present invention relates to a stabilized self-emulsifying system, comprising a therapeutically effective amount of o-(chloroacetylcarbamoyl)fumigillol, a pharmaceutically acceptable carrier and a stabilizing component, wherein the pharmaceutically acceptable carrier comprises an oily constituent and at least one surfactant. The stabilizing component comprises from about 1% to about 15% water relative to the weight of the self-emulsifying system, an acid, an adsorbent, or a complex-forming agent.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: November 13, 2001
    Assignee: Abbott Laboratories
    Inventors: Rong Ron Liu, Zheng Wang