Abstract: The structure of the Syringe Holder and Applicator provides an inner cylindrical tube adapted to have a hypodermic syringe inserted and held therein. This inner tubular syringe holder is slideably contained within an outer cylindrical tube. A cylindrical coil-spring retainer tube is also contained within the outer tube at the distal end of the outer tube's cylindrical cavity, leaving a considerable portion of the outer tube's cylindrical cavity free for occupation by the inner tubular syringe holder. The body of the outer tube is provided with a trigger mechanism which will automatically engage and lock the inner tubular syringe holder in a retracted position within the outer tube's cylindrical cavity when the inner tubular syringe holder is retracted toward the distal end of the outer tube's cylindrical cavity. The trigger mechanism is designed to, when pressed inward, release the inner tubular syringe holder for travel within the outer tube's cylindrical cavity.