Patents Represented by Law Firm Hale and Dorr
  • Patent number: 8071559
    Abstract: The application relates to methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the mir17-92 cluster. The application further relates to screening methods to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.
    Type: Grant
    Filed: May 2, 2006
    Date of Patent: December 6, 2011
    Assignees: Cold Spring Harbor Laboratory, University of North Carolina
    Inventors: Gregory J. Hannon, Scott Hammond, Lin He, John Michael Thomson, Summer Goodson
  • Patent number: 8073848
    Abstract: A method of selecting and presenting content based on inferred user preferences is provided. The method includes providing a set of content items having associated descriptive terms and receiving search inputs from an input device and presenting a corresponding subset of content items. The method includes receiving selection actions of content items and analyzing the descriptive terms associated with the selected content items to learn a composite set of preferred descriptive terms of the plurality of users of the input device. The method includes inferring preferences of individual users from the composite set of preferred descriptive terms by decomposing the composite set of preferred descriptive terms into individual sets of preferred descriptive terms. The decomposition act utilizes prespecified statistical models of preferences.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: December 6, 2011
    Assignee: Veveo, Inc.
    Inventors: Murali Aravamudan, Ajit Rajasekharan, Kajamalai G. Ramakrishnan
  • Patent number: 8067112
    Abstract: There is provided a stacked lithium secondary battery in which a plurality of cathode plates and a plurality of anode plates are alternatively facing each other, and its fabrication method. The method comprises adhering a plurality of anode plates to a portion of one surface of a separator onto which the anode plates are neighboring one another, adhering a plurality of cathode plates to a portion of the other surface of the separator onto which the cathode plates are neighboring one another, covering either the cathode or anode plates with the separator by folding the portion to which no electrode plate is adhered, successively folding the separator in a fixed one-direction along folding lines formed between the electrode plates to obtain a stacked body, and housing the obtained stacked body within a pouch, followed by injection of an electrolyte solution and packaging.
    Type: Grant
    Filed: January 27, 2004
    Date of Patent: November 29, 2011
    Assignee: Enerland Co., Ltd.
    Inventor: Whanjin Roh
  • Patent number: 8067414
    Abstract: The invention provides compositions and kits comprising at least one nitric oxide enhancing prostaglandin compound or a pharmaceutically acceptable salt thereof, and, optionally, at least one nitric oxide enhancing compound and/or at least one therapeutic agent. The invention also provides methods for (a) treating ophthalmic disorders; (b) treating cerebrovascular disorders; (c) treating cardiovascular disorders; (d) treating benign prostatic hyperplasia (BPH); (e) treating peptic ulcers; (e) treating sexual dysfunctions and (f) inducing abortions. The nitric oxide enhancing prostaglandin compounds comprise at least one heterocyclic nitric oxide donor group and/or at least one nitroxide group.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: November 29, 2011
    Assignee: NiCox S.A.
    Inventor: David S. Garvey
  • Patent number: 8067464
    Abstract: The invention describes novel compositions comprising at least one apocynin compound or a pharmaceutically acceptable salt thereof, and at least one nitric oxide donor, and, optionally, at least one therapeutic agent. The invention also provides novel kits comprising at least one apocynin compound or a pharmaceutically acceptable salt thereof, and at least one nitric oxide donor compound, and, optionally, at least one therapeutic agent. The invention also provides methods for (a) treating cardiovascular diseases; (b) treating renovascular diseases; (c) treating diabetes; (d) treating diseases resulting from oxidative stress; (e) treating endothelial dysfunctions; (f) treating diseases caused by endothelial dysfunctions; (g) treating gastrointestinal disorders; (h) treating inflammatory disorders; and (j) treating respiratory disorders; and (k) treating peripheral vascular diseases. The apocynin compound may preferably be apocynin.
    Type: Grant
    Filed: October 3, 2005
    Date of Patent: November 29, 2011
    Assignee: Nitromed, Inc.
    Inventor: David S. Garvey
  • Patent number: 8069486
    Abstract: Capturing information associated with a document is disclosed. An indication that a request to print a document is being transmitted is observed in network traffic associated with a printer. At a node other than the printer, data associated with the observed network traffic is processed to determine information associated with the request to print the document.
    Type: Grant
    Filed: March 27, 2006
    Date of Patent: November 29, 2011
    Assignee: Symantec Corporation
    Inventors: Brian Hernacki, Sourabh Satish
  • Patent number: 8069377
    Abstract: An integrated circuit device (for example, a logic device or a memory device (such as, a discrete memory device)), including a memory cell array having a plurality of memory cells arranged in a matrix of rows and columns, multiplexer circuitry, coupled to the memory cell array, wherein the multiplexer circuitry includes a plurality of data multiplexers, each data multiplexer having a plurality of inputs, including (i) a first input to receive write data which is representative of data to be written into the memory cells of the memory cell array in response to a write operation, and (ii) a second input to receive read data which is representative of data read from memory cells of the memory cell array, and an associated output to responsively output data from one of the plurality of inputs, and syndrome generation circuitry, coupled to the multiplexer circuitry, to generate: (i) a write data syndrome vector using the write data and (ii) a read data syndrome vector using the read data.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: November 29, 2011
    Assignee: Micron Technology, Inc.
    Inventor: Anant Pratap Singh
  • Patent number: 8064909
    Abstract: Systems and methods are provided that allow inter-working between communication networks for the delivery of service to mobile nodes. A gateway is provided that communicates with a femto cell to extend service to an area that otherwise does not receive coverage from a service provider. The femto cell is a small scale base station used to provide coverage over a small area (such as a home or business), and connect to a home or enterprise network. The femto cell provides service for a mobile node and a gateway permits communication over a broadband network. The gateway integrates the mobile nodes connecting via a femto cell into the service provider's network. The gateway also allows provisioning of services and applications, control of service levels, and provides seamless handoffs to macro base stations and other types of access technologies such as Wi-Fi.
    Type: Grant
    Filed: October 27, 2008
    Date of Patent: November 22, 2011
    Assignee: Cisco Technology, Inc.
    Inventors: Vincent Spinelli, John Depietro, Vijay Kathuria, Mohan Rangan, Rajat Ghai, Ashraf M. Dahod, Rajesh Ramankutty, Sanil Kumar Puthiyandyil, Shaji E. Radhakrishnan
  • Patent number: 8063820
    Abstract: The disclosed subject matter generally relates to hybrid positioning systems and methods, more specifically, systems and methods of integrating a wireless local area network (WLAN) based positioning system (WLAN-PS) and a satellite positioning system (SPS) to improve accuracy of location estimates by selecting the best set of measurements from both systems.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: November 22, 2011
    Assignee: Skyhook Wireless, Inc.
    Inventor: Farshid Alizadeh-Shabdiz
  • Patent number: 8065217
    Abstract: A computer-implemented system and method are described for real-time portfolio balancing and/or optimization of portfolio holdings, preferably in Alternative Trading Systems (ATSs), that reduces execution risk and legging risk. The computer-implemented system and method also incorporate cash constraints to assist in reducing execution risks. A computer-implemented system and method include advantages such as exposure to broad market liquidity throughout the trading day, being dynamic so that a strategy can be adjusted depending on market conditions, the reduction of execution and legging risks, optimal fills, and limited market impact.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: November 22, 2011
    Assignee: Bids Trading, L.P.
    Inventor: Mark Beddis
  • Patent number: 8063216
    Abstract: The present invention describes Photolabile Compounds methods for use of the compounds. The Photolabile Compounds have a photoreleasable ligand, which can be biologically active, and which is photoreleased from the compound upon exposure to light. In one embodiment, the light is visible light, which is not detrimental to the viability of biological samples, such as cells and tissues, in which the released organic molecule is bioactive and can have a therapeutic effect.
    Type: Grant
    Filed: December 14, 2004
    Date of Patent: November 22, 2011
    Assignees: The Trustees of Columbia University in the City of New York, Universidad de Buenos Aires
    Inventors: Roberto Etchenique, Rafael Yuste, Luis Baraldo
  • Patent number: 8064408
    Abstract: Devices and methods are provided for directionally receiving and/or transmitting acoustic waves and/or radio waves for use in applications such as wireless communications systems and/or radar. High directional gain and spatial selectivity are achieved while employing an array of receiving antennas that is small as measured in units of the wavelength of radio waves being received or transmitted, especially in the case of spatially oversampled arrays. Frequency/wavenumber, multi-dimensional spectrum analysis, as well as one-dimensional frequency spectrum analysis can be performed.
    Type: Grant
    Filed: February 17, 2009
    Date of Patent: November 22, 2011
    Assignee: Hobbit Wave
    Inventor: Harvey C. Woodsum
  • Patent number: 8065489
    Abstract: Method and apparatus for managing concurrent access among computers to a bitmap stored on disk storage. In some examples, a command is received from a requesting computer of the computers, the command indicating that one or more bits in the bitmap are to be cleared. The bitmap as stored on the disk storage is updated responsive to the command to clear the one or more bits in the bitmap. Synchronization data associated with the bitmap is stored. The synchronization data is configured to distinguish between a current generation and a previous generation of the bitmap, and to specify an action to be performed in response to receiving a subsequent command for accessing the bitmap if the subsequent command identifies a previous generation.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: November 22, 2011
    Assignee: Symantec Corporation
    Inventor: Roger John Cummings
  • Patent number: 8065179
    Abstract: A method and apparatus for providing a utility based revenue stream for a security software subscription at a client computer is provided. In one embodiment, the method for providing a utility based revenue stream for a security software subscription at a client computer comprises analyzing a security activity log based on a utility metric to produce an analysis result and determining a value for the security software subscription based on the analysis result.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: November 22, 2011
    Assignee: Symantec Corporation
    Inventor: Neeran Mohan Karnik
  • Patent number: 8064274
    Abstract: A method of generating a voltage as well as an integrated circuit device (e.g., a logic device or a memory device) having a memory cell array which includes (i) a plurality of memory cells, wherein each memory cell array including (i) a plurality of memory cells, arranged in a matrix of rows and columns, and (ii) a plurality of bit lines, wherein each bit line includes a plurality of memory cells. The integrated circuit further includes voltage generation circuitry, coupled to a plurality of the bit lines, to (i) apply a first voltage to a first group of associated bit lines, and (ii) apply a second voltage to a second group of associated bit lines, and (iii) generate a third voltage by connecting the first group of associated bit lines and the second group of associated bit lines, and (iv) output the third voltage. Also, disclosed is a method of operation and/or control of such an integrated circuit device as well as such voltage generation circuitry.
    Type: Grant
    Filed: May 27, 2008
    Date of Patent: November 22, 2011
    Assignee: Micron Technology, Inc.
    Inventors: David Fisch, Philippe Bauser
  • Patent number: 8064493
    Abstract: A surface emitting photonic device including a substrate; and a waveguide structure on the substrate. The waveguide structure includes an active region along its longitudinal axis and the active region is for generating light. The waveguide structure also has a trench formed therein transverse to the active region and defining a first wall forming an angled facet at one end of the active region, the first wall having a normal that is at a non-parallel angle relative to the longitudinal axis of the waveguide structure. The trench also defines a second wall located opposite the first wall.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: November 22, 2011
    Assignee: BinOptics Corporation
    Inventors: Alex Behfar, Cristian Stagarescu
  • Patent number: 8057936
    Abstract: Nanoscale ion storage materials are provided that exhibit unique properties measurably distinct from their larger scale counterparts. For example, the nanoscale materials can exhibit increased electronic conductivity, improved electromechanical stability, increased rate of intercalation, and/or an extended range of solid solution. Useful nanoscale materials include alkaline transition metal phosphates, such as LiMPO4, where M is one or more transition metals. The nanoscale ion storage materials are useful for producing devices such as high energy and high power storage batteries, battery-capacitor hybrid devices, and high rate electrochromic devices.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: November 15, 2011
    Assignee: A123 Systems, Inc.
    Inventors: Yet-Ming Chiang, Antoni S. Gozdz, Martin W. Payne
  • Patent number: 8057931
    Abstract: A battery including: a plurality of battery cells arranged side-by-side, each battery cell including a terminal tab for delivering power from the cell; a bus plate made of an electrically non-conductive material, the bus plate also having an array of holes formed therein, the array of holes defining a plurality of hole pairs, wherein the terminal tab from each cell of the plurality of cells extends through a corresponding different hole in the array of holes, wherein for each hole pair of the plurality of hole pairs, the terminal tabs extending through that hole pair are folded one over the other to produce overlapping tabs for that hole pair; and a plurality of clamps each of which clamps together the overlapping tabs of a corresponding different hole pair.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: November 15, 2011
    Assignee: Securaplane Technologies, Inc.
    Inventor: James B. Bjork
  • Patent number: 8060112
    Abstract: The present invention provides a system and mobile device for providing geographic information to a user. The system includes a mobile device that is wirelessly connected to a geographic database. The mobile device includes a plurality of sensors for determining a first location and a first direction. A controller is adapted to provide information requested based on local queries and distal queries. In addition, the controller can respond to thematic queries of each variety, wherein the database search is limited to objects, entities or features that fit within a selected theme. Finally, the controller is adapted to select and order query results based upon two- and three-dimensional query windows.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: November 15, 2011
    Assignee: Intellient Spatial Technologies, Inc.
    Inventors: Christopher E. Frank, Michael H. Grillo
  • Patent number: 8060703
    Abstract: Techniques for allocating/reducing storage required for one or more virtual machines are disclosed. In one particular exemplary embodiment, the techniques may be realized as a method for allocating storage for one or more virtual machines. The method may comprise providing one or more virtual machines. The method may also comprise creating one or more master images containing one or more commonly used blocks. The method may also comprise creating one or more Copy on Write volumes, where each Copy on Write volume may be associated with at least one of the one or more virtual machines and at least one of the one or more master images, and wherein updated blocks may be stored in at least one of the one or more Copy on Write volumes, thereby reducing storage required for one or more virtual machines.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: November 15, 2011
    Assignee: Symantec Corporation
    Inventors: Komal Desai, Jonathan Purcell, Bruce Montague, Viswesvaran Janakiraman, Douglas Fallstrom, Rajeev Bharadhwaj