Abstract: A stabilized thermoplastic composition comprised of polyvinyl chloride or mixed polymers containing mainly vinyl chloride units together with stabilizers and other conventional additives employed in thermoplastic compositions, which have as major stabilizer component, a content of 0.02 to 5 parts by weight of aliphatic polyhydroxyl compounds containing 4 to 6 OH-groups per 100 parts by weight of polymer. These polyhydroxyl compounds should contain at least one carboxyl and/or carbonyl group and/or double bond. Suitable compounds are gluconic acid, glucuronic acid, ketogluconic acid, ascorbic acid or the alkali metal salts or alkaline earth salts of the mentioned acids.Other conventional processing additives may be present. The invention concerns also a process for the manufacture of pipes, profiles, foils, hollow parts by hot forming, with the use of the mentioned additives, and the additional use of paraffin, free fatty acid, epoxidized soybean oil or higher molecular weight ester wax.

Abstract: A novel process for the preparation of 7-acylamino-3-(thio-substituted)-methyl-3-cephem-4-carboxylic acid 1-oxide derivatives comprising reacting a 7-acylamino-3-bromomethyl-3-cephem-4-carboxylic acid-1-oxide derivative with a silylated thiol of the formulaR--S--Si(CH.sub.3).sub.3 Iwherein R is an organic group, preferably a 5- or 6-membered heterocyclic group, which reaction is preferably carried out in the presence of an inert organic solvent at a temperature between -20.degree. and 80.degree. C. to obtain the corresponding 7-acylamino-3-(R-thiomethyl)-3-cephem-4-carboxylic acid-1-oxide derivatives, which are valuable intermediates in methods for the preparation of therapeutically active cephalosporins.

Abstract: This invention relates to a process for determining the uric acid content of biological material by contacting the biological material with a reagent composition comprised of uricase, catalase, aldehyde dehydrogenase, a lower alkanol, and nicotinamide adenine dinucleotide or nicotinamide adenine dinucleotied phosphate, the improvement which comprises determining the uric acid content in the presence of 2-mercaptosuccinic acid.

Abstract: Compounds of the formula ##STR1## wherein A and B, together with each other and the respective carbon atoms to which they are attached, form a phenyl or pyridine ring;R.sub.1 is hydrogen, halogen, amino, nitro, alkyl of 1 to 3 carbon atoms or alkoxy of 1 to 3 carbon atoms;R.sub.2 is hydrogen or alkoxy of 1 to 3 carbon atoms;D is alkylene of 3 to 4 carbon atoms or hydroxy(alkylene of 3 to 4 carbon atoms);R.sub.3 and R.sub.5, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 3 carbon atoms;R.sub.4 is hydrogen or alkoxy of 1 to 3 carbon atoms; andR.sub.6 is straight or branched alkyl of 1 to 6 carbon atoms or --E--R.sub.7 ;where E is straight alkylene of 2 to 4 carbon atoms or hydroxy-substituted straight alkylene of 2 to 4 carbon atoms, andR.sub.7 is ##STR2## where R.sub.8 and R.sub.

Abstract: Compounds of the formula ##STR1## wherein A is phenyl, 4-hydroxy-phenyl, 2-thienyl or 3,4-dihydroxy-phenyl; andR is ##STR2## where R.sub.1 and R.sub.2, which may be identical to or different from each other, are each methylmercapto or amino;Z' is oxygen, sulfur or .dbd.NR.sub.3 ;R.sub.3 is hydrogen, alkyl of 1 to 3 carbon atoms or hydroxy-(alkyl of 1 to 3 carbon atoms);R.sub.4 is hydrogen, hydroxyl, hydroxymethyl or methyl;n is 2, 3 or 4;Y is --SO.sub.2 NH--, --SO-- or --SO.sub.2 --;Z is straight or branched alkylene of 1 to 3 carbon atoms;X is hydroxyl, aminocarbonyl, aminosulfonyl, formylamino, acetylamino, amino, methylsulfinyl, methylsulfonyl or ##STR3## or --Y--Z--X is ##STR4## and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as the salts are useful as antibiotics.

Abstract: An apparatus for producing a cage made of castable or injection moldable material for cylindrical rollers in which the pockets of the cage are defined by webs having projections projecting into the pockets at their longitudinal sides for radially retaining the rollers comprising slide plates radially moveable for forming the roller pockets, each slide plate being formed of several partial slide plates, the end faces of the slide plates having cover plates arranged thereon to cover the connection juncture between the partial slide plates and secured to one of the partial slide plates.

Abstract: An improved process for treating coal tar pitch to form anisotropic carbon comprising treating coal tar pitch with picric acid, recovering the resulting picrates, decomposing the picrates and heating the resulting aromatic hydrocarbons to obtain anisotropic carbon in less time.

Abstract: Compounds of the formula ##STR1## wherein Het is ##STR2## n is an integer from 1 to 4, inclusive, preferably 2 or 3, R.sub.1 is H or acyl,R.sub.2 is H, R.sub.1 O, --NHSO.sub.2 R.sub.7, --NHCOR.sub.8, --NHCONHR.sub.8, --NH--CH.sub.2 --C.sub.6 H.sub.4 --R.sub.9, --CH.sub.2 OH, --CH.sub.2 SO.sub.2 R.sub.7, --CONHR.sub.8, halogen or --CN,R.sub.3 is H, halogen, R.sub.7 or --OR.sub.7,R.sub.2 and R.sub.3 together with each other are ##STR3## R.sub.4 is H, --CH.sub.3 or --C.sub.2 H.sub.5, R.sub.5 and R.sub.6 are each H or --CH.sub.3,R.sub.7 is C.sub.1 -C.sub.4 alkyl,R.sub.8 is H or C.sub.1 -C.sub.4 alkyl,R.sub.9 is H, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy optionally interrupted by oxygen,R.sub.10 and R.sub.12 are each H, CH.sub.3, Cl or OCH.sub.3, or together methylenedioxy,X is ##STR4## or N, and Z is --CH.sub.2 or --CO;in the form of racemates, enantiomers, diastereoisomeric antipode pairs, and non-toxic, pharmacologically acceptable acid addition salts thereof.

Abstract: Cyanacrylic acid ester based glues with a reduced setting time comprising a cyanacrylic acid ester and from 0.005% to 3% by weight, based on the cyanacrylic acid ester of a polyoxyalkylene glycol diester having the formula ##STR1## wherein x is an integer from 5 to 80, Alk is an alkylene having from 2 to 4 carbon atoms, and R.sub.1 and R.sub.2 represent members selected from the group consisting of hydroxyl, halogen, lower alkoxy, alkoxyalkyl having from 3 to 12 carbon atoms, alkyl having from 1 to 12 carbon atoms, cyanoalkyl having from 1 to 12 carbon atoms, haloalkyl having from 1 to 12 carbon atoms, nitroalkyl having from 1 to 12 carbon atoms, alkenyl having from 2 to 12 carbon atoms, alkynyl having from 2 to 12 carbon atoms, cycloalkyl having from 3 to 12 carbon atoms, phenyl, nitrophenyl, halophenyl, phenylalkyl having from 1 to 6 carbon atoms in the alkyl and alkylphenyl having from 1 to 6 carbon atoms in the alkyl.

Abstract: A laminating and coating adhesive based on an aqueous dispersion of(1) a copolymer of a vinyl ester, and/or an acrylic acid ester, and/or a further monomer and an ethylenically-unsaturated functional group-containing monomer having from 3 to 18 carbon atoms and hydroxy and carbonyl groups as functional groups, such as a monocarboxylic acid or dicarboxylic acid and/or N-methylol-(meth)-acrylamide,(2) an epoxy compound, and(3) an amine hardener.The adhesive gives a laminate bond with especially high resistance to peeling even in the case of thermal stress and/or in the presence of water.

Abstract: The subject of the invention is a microsuspension polymerization in water of vinyl chloride, which is carried out in the presence of monomer-soluble radical-initiators and emulsifiers. According to the invention, from about 0.01 to 0.5% by weight, based on the weight of the water, of polymers containing mono-basic or dibasic carboxylic acid units and/or salts thereof are added. Furthermore, in a preferred embodiment, emulsifiers containing perfluorinated alkyl groups are also used. Stabilization of the microsuspension latex, which is per se sensitive to shearing action, and reduction in the amount of emulsifiers used are achieved.

Abstract: An improved process for the preparation of 5-chloro-indole comprising reacting indoline in a chlorine-inert organic solvent with an acylating agent of an organic carboxylic acid to obtain the corresponding 1-acyl-indoline, reacting the latter in the presence of water and a basic agent with chlorine to form 5-chloro-1-acyl-indoline, subjecting the latter to saponification to obtain 5-chloro-indoline and reacting the latter in a water-immiscible organic solvent by heating with an aromatic nitrocompound in the presence of a finely powdered ruthenium catalyst to form 5-chloro-indole in excellent yields.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, methyl or ethyl;R.sub.2 is hydrogen or chlorine;R.sub.3 is hydrogen or chlorine; andR.sub.4 is pyrrolidino, piperidino, 2-methyl-piperidino, 2-ethyl-piperidino, 2,6-dimethyl-piperidino or morpholino;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as gastric secretion inhibitors and anti-ulcerogenics.

Abstract: The tridecapeptide of the formulaH-Met-Ser-Tyr-Asn-Leu-Leu-Gly-Phe-Leu-Gln-Arg-Ser-Ser-OHand the use thereof as a hapten, tracer or antibody.

Abstract: A novel process for the preparation of 3-amino-steroids of the formula ##STR1## wherein X is selected from the group consisting of ##STR2## and the wavy lines indicate that the substituents may be in the .alpha.- or .beta.-position and their non-toxic, pharmaceutically acceptable acid addition salts in good yields and novel intermediates.

Abstract: A process for the preparation of stable suspensions and powders of stable microcapsules containing at least one active material having a variable porosity comprising preparing a colloidal solution of equal parts by weight of gelatin and acacia gum with a total concentration of 4 to 6% by weight of the final emulsion, preparing an oil solution, suspension or emulsion of the active material at a concentration of 1 to 5% by weight of the final emulsion and containing a variable amount of organosoluble ethyl hydroxyethylcellulose, mixing the said two compositions with stirring at a temperature near 50.degree. C. in the presence of an emulsifying agent to form an "oil in water" emulsion, effecting consecutively coacervation and microencapsulation of the emulsified droplets containing the active material by adjusting the pH to 4.2 to 4.4 by addition of an acid and then cooling the mixture to about 20.degree. C.

Abstract: New cytostatic compounds based on isocyanuric acid derivatives having 2 or 3 epoxide group containing substituents on ring nitrogen atoms, of which at least one differs from a glycidyl, having the formula ##STR1## wherein Oxiranyl is the same or different and has the formula ##STR2## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different and members selected from the group consisting of hydrogen, alkyl, haloalkyl, hydroxyalkyl and alkoxyalkyl and n in an integer from 1 to 8, with the proviso that if n is 1 in all oxiranyl groups, at least one of R.sub.1 or R.sub.3 is other than hydrogen, and R is a member selected from the group consisting of oxiranyl as defined above, hydrogen, alkyl, alkenyl, hydrocarbon aryl, hydrocarbon aralkyl, hydrocarbon alkaryl, cycloalkyl, and cycloalkenyl, optionally containing substituents.When R.sub.1, R.sub.2 and/or R.sub.3 denote alkyl or substituted alkyl in the oxiranyl radical, the alkyl radicals preferably have from 1 to 4 carbon atoms.

Abstract: Compounds of the formula ##STR1## wherein R is selected from the group consisting of hydrogen and groups easily removable by acid hydrolysis or hydrogenolysis, R' is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl and alkynyl of 2 to 4 carbon atoms and groups easily removable by acid hydrolysis or hydrogenolysis, A is selected from the group consisting of hydrogen, alkali metal and equivalents of an alkaline earth metal or magnesium and an organic amine base with the proviso that when R' is a group easily removable by acid hydrolysis or hydrogenolysis, R is also and when R' is hydrogen, R also is hydrogen and the wavy line means the OR' group may be in either one of the two possible syn or anti positions having antibiotic activity and process for their preparation.

Abstract: This invention relates to a process for the preparation of a concentrate containing sterol compounds of natural origin, which concentrate is suitable as a starting material for the transformation of sterol compounds by fermentation, which comprises the steps of:(a) transesterifying distillation residues from the processing of natural fats and/or oils with a lower alcohol; and(b) subjecting the product of step (a) to molecular distillation to produce a main fraction having a content of up to about 50 percent by weight of sterol compounds.The invention also relates to sterol concentrates produced thereby and their transformation to valuable secondary products.

Abstract: Novel syn isomers of 7-[2-(2-amino-4-thiazolyl)-2-(carboxymethyloxyimino)-acetamido]-ceph-3-eme -4-carboxylic acid compounds of the formula ##STR1## wherein R is selected from the group consisting of alkyl of 1 to 3 carbon atoms and --CH.sub.2 --S--R.sub.1, R.sub.1 is an optionally substituted heterocyclic of 5 to 6 chain components with 1 to 4 heteroatoms selected from the group consisting of oxygen, sulfur and nitrogen, A is selected from the group consisting of hydrogen, alkali metal, alkaline earth metal, magnesium, --NH.sub.4, an easily cleavable ester and a non-toxic, pharmaceutically acceptable organic amine, A.sub.1 is selected from the group consisting of alkyl of 1 to 3 carbon atoms, hydrogen, alkali metal, alkaline earth metal, magnesium, --NH.sub.4, an easily cleavable ester and a non-toxic, pharmaceutically acceptable organic amine and non-toxic, pharmaceutically acceptable acid addition salts thereof having antibiotic activity and their preparation and intermediates therefor.