Patents Represented by Law Firm Hammond & Littell, Weissenberger & Dippert
  • Patent number: 4558061
    Abstract: Compounds of the formula ##STR1## wherein n is 1 or 2, R.sub.1 is hydrogen, --CO--R.sub.2 or --SO.sub.2 R.sub.3,R.sub.2 is hydrogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms or (alkyl of 1 to 4 carbon atoms)amino, andR.sub.3 is alkyl of 1 to 4 carbon atoms,and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bronchospasmolytics.
    Type: Grant
    Filed: July 6, 1984
    Date of Patent: December 10, 1985
    Assignee: Boehringer Ingelheim KG
    Inventors: Anton Mentrup, Kurt Schromm, Ernst-Otto Renth, Gojko Muacevic, Armin Fugner
  • Patent number: 4555426
    Abstract: Novel preformed, laminated plastic panels as semi-finished products comprising a plurality of individual laminated thermoplastic layers or thermoplastic layers arranged in partly differing orientations reinforced with unidirectionally preoriented short fibers comprising 20 to 80% of the layer volume, said laminate capable of being molded and/or deep drawn by hot pressing and/or hot molding at 70.degree. to 400.degree. C. and at a pressure of approximately 40 bar.
    Type: Grant
    Filed: October 19, 1983
    Date of Patent: November 26, 1985
    Assignees: Dornier GmbH, Technochemie GmbH-Verfahrenstechnik
    Inventors: Siegfried Roth, Horst Stenzenberger
  • Patent number: 4555511
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of 1 to 6 carbon atoms or phenyl (alkyl of 1 to 6 carbon atoms);R.sub.2 is hydrogen, alkyl of 1 to 4 carbon atoms or phenyl (alkyl of 1 to 6 carbon atoms);R.sub.3 is hydrogen or alkyl of 1 to 6 carbon atoms; and their use as antihypertensives.
    Type: Grant
    Filed: January 19, 1984
    Date of Patent: November 26, 1985
    Assignee: Boehringer Ingelheim KG
    Inventors: Gerd Schnorrenberg, Otto Roos, Walter Losel, Ingrid Wiedemann, Wolfram Gaida, Wolfgang Hoefke
  • Patent number: 4555359
    Abstract: Trimethylbicyclo [4.3.0] non-1-ene derivatives are fragrant substances which are suitable for use alone and in perfume and odorant compositions. Methods of preparation and representive compositions are also disclosed.
    Type: Grant
    Filed: January 18, 1983
    Date of Patent: November 26, 1985
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Klaus Bruns, Ursula Weber
  • Patent number: 4551464
    Abstract: Compounds of the formula ##STR1## wherein n is 0 or 1;A is methylene, vinylene or ethylene optionally substituted by lower alkyl;B is alkylene;R.sub.1 is an optionally substituted alkyl, phenyl or naphthyl group, or a cycloalkyl or pyridyl group; andR.sub.2 is hydrogen or acyl;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antithrombotics.
    Type: Grant
    Filed: January 26, 1984
    Date of Patent: November 5, 1985
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Erich Muller, Josef Nickl, Berthold Narr, Josef Roch, Walter Haarmann, Johannes M. Weisenberger
  • Patent number: 4550106
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is amino, acetylamino, hydroxymethyl, methoxymethyl or ##STR2## R.sub.2 and R.sub.3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, methoxy, methyl or ethyl;R.sub.4 is straight or branched alkyl of 1 to 3 carbon atoms; andR.sub.5 and R.sub.6, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered heterocyclic ring where, in the case of a 6-membered ring, a --CH.sub.2 -group in the ring may be replaced by an oxygen atom,and non-toxic, pharmacologically acceptable salts thereof. The compounds as well as their salts are useful as antidepressants.
    Type: Grant
    Filed: July 23, 1984
    Date of Patent: October 29, 1985
    Assignee: Boehringer Ingelheim KG
    Inventors: Claus Schneider, Gerhard Walther, Karl-Heinz Weber, Wolf D. Bechtel, Karin Boke-Kuhn
  • Patent number: 4548944
    Abstract: Compounds of the tautomeric formula ##STR1## wherein R, R.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 4 carbon atoms;R.sub.3 is straight or branched alkyl, optionally interrupted by heteroatoms such as oxygen, sulfur or nitrogen; straight or branched alkenyl; alkynyl; cyano; cycloalkyl or cycloaliphatic alkyl; a bicyclic group; aryl; or a heterocyclic group; orR.sub.2 and R.sub.3, together with each other and the nitrogen atoms to which they are attached, form a heterocyclic group;R.sub.4 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms; andHet is a substituted or unsubstituted heterocycle containing two or three heteroatoms;tautomers thereof, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as anti-ulcerogenics.
    Type: Grant
    Filed: February 10, 1983
    Date of Patent: October 22, 1985
    Assignee: Istituto de Angeli S.p.A.
    Inventors: Giuseppe Bietti, Enzo Cereda, Arturo Donetti, Piero del Soldato, Antonio Giachetti, Rosamaria Micheletti
  • Patent number: 4548825
    Abstract: This invention is directed to a method for the non-contact application of letters or symbols to the exterior surfaces of uncoated tablets or uncoated tablet cores, which comprises dotting color solution or suspension by means of an ink-jet printer in specific quantity in the form of discrete droplets of specific volume onto the exterior surfaces of the uncoated tablets or uncoated tablet cores.
    Type: Grant
    Filed: October 3, 1983
    Date of Patent: October 22, 1985
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Gunther Voss, Peter Gruber
  • Patent number: 4547359
    Abstract: A novel divisible delayed release pharmaceutical tablet, wherein the rate of release of active ingredient is independent of the size and nature of the total surface area, and the fragments of which have the same characteristics of release of active ingredient as the undivided tablet.
    Type: Grant
    Filed: March 21, 1984
    Date of Patent: October 15, 1985
    Assignee: Boehringer Ingelheim KG
    Inventors: Bernd Zierenberg, Arun R. Gupte
  • Patent number: 4546102
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of 1 to 4 carbon atoms or trifluoromethyl;R.sub.2, R.sub.3 and R.sub.4 are each independently hydrogen, methyl or ethyl;R.sub.5 is hydrogen, alkyl of 1 to 8 carbon atoms, phenyl-(alkyl of 1 to 8 carbon atoms), cycloalkyl of 3 to 7 carbon atoms, (alkoxy of 1 to 4 carbon atoms) carbonyl-methyl, phenyl, substituted phenyl, naphthyl or substituted naphthyl; orR.sub.4 and R.sub.5, together with each other, are alkylene of 4 to 5 carbon atoms, optionally interrupted by --O-- or --NR.sub.6 --, where R.sub.6 is alkyl of 1 to 4 carbon atoms;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as cardiotonics.
    Type: Grant
    Filed: October 31, 1983
    Date of Patent: October 8, 1985
    Assignee: Boehringer Ingelheim KG
    Inventors: Ernst-Otto Renth, Anton Mentrup, Kurt Schromm, Werner Traunecker, Richard Reichl
  • Patent number: 4545930
    Abstract: This invention is directed to terpene derivatives. More particularly, this invention relates to a mixture of isomers of the formula ##STR1## wherein R.sub.1 and R.sub.2, which are different from each other, are each methyl or isopropyl, the preparation thereof, and perfume compositions containing them.
    Type: Grant
    Filed: July 15, 1982
    Date of Patent: October 8, 1985
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Horst Upadek, Klaus Bruns
  • Patent number: 4541551
    Abstract: A sealing top for containers for powdered or granular materials which permits controlled discharge of the container contents without clogging and which is provided with a valved opening by which the sealing top may be opened and closed.
    Type: Grant
    Filed: September 21, 1981
    Date of Patent: September 17, 1985
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Peter Vierkotter, Erich Turk, Bernd-Dieter Holdt, Ronald Menke
  • Patent number: 4539323
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each independently hydrogen, straight or branched alkyl of 1 to 8 carbon atoms or arylmethyl; orR.sub.1 and R.sub.2, together with each other, are --(CH.sub.2).sub.4 or --(CH.sub.2).sub.5 --; andR.sub.3 and R.sub.4, which may be identical to or different from each other, are each independently hydrogen, straight or branched alkyl of 1 to 4 carbon atoms or arylmethyl; orR.sub.3 and R.sub.4, together with each other, are --CH.sub.3 -- or --CH.sub.2 --CH.sub.2 --;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful for the treatment of cardiovascular diseases, especially hypertension.
    Type: Grant
    Filed: September 14, 1983
    Date of Patent: September 3, 1985
    Assignee: Boehringer Ingelheim KG
    Inventors: Anton Mentrup, Ernst-Otto Renth, Kurt Schromm, Wolfgang Hoefke, Wolfram Gaida
  • Patent number: 4539011
    Abstract: An artificial fireplace log consisting of a difficultly burnable sleeve filled with an easily flammable material and having an external ignition strip of easily flammable material. The sleeve has prefabricated discontinuities acting as ignition points.
    Type: Grant
    Filed: July 12, 1983
    Date of Patent: September 3, 1985
    Assignee: Anasco Gesellschaft mit beschrankter Haftung
    Inventor: Gunther Kretzschmann
  • Patent number: 4537790
    Abstract: The present invention relates to a process for growing cell cultures of diploid cells. The process comprises the steps of(a) introducing cell culture medium into a container containing cell support prepared by applying to glass or polysaccharide base support a solution of thermosetting plastic material comprising the reaction product of an aldehyde with a polyvinyl alcohol and then subjecting said support thus-coated to the effect of heat under sufficient conditions to permit hardening of said thermosetting plastic material and the sterilization of the thus-coated support;(b) adding human or animal diploid cells to the culture medium of step (a) to form a cell-containing culture medium; and(c) maintaining the cell-containing culture medium of step (b) under cell growth conditions.
    Type: Grant
    Filed: May 11, 1983
    Date of Patent: August 27, 1985
    Assignee: Institut Pasteur
    Inventors: Florian Horodniceanu, Raphael Le Fur
  • Patent number: 4536402
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is phenyl, halo- and/or methyl-substituted phenyl or pyridinyl;R.sub.2 is hydrogen, straight or branched alkyl of 1 to 4 carbon atoms, 2- or 3-hydroxy-(alkyl of 2 to 3 carbon atoms) or 2- or 3-dimethylamino-(alkyl of 2 to 3 carbon atoms);R.sub.3 is hydrogen or alkyl of 1 to 3 carbon atoms; andR.sub.4 is hydrogen, chlorine or methyl.The compounds are useful as anticonvulsants.
    Type: Grant
    Filed: November 29, 1984
    Date of Patent: August 20, 1985
    Assignee: Dr. Karl Thomae Gesellschaft mit beschranter Haftung
    Inventors: Wolfhard Engel, Eckhart Bauer, Gunter Trummlitz, Peter Danneberg, Joachim Kahling
  • Patent number: 4533664
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, methyl, methoxy, fluorine or chlorine; andR.sub.2 is hydrogen, methyl, ethyl or n-propyl;and non-toxic, pharmacologically acceptable salts thereof formed with an inorganic or organic base. The compounds as well as the salts are useful as antithrombotics.
    Type: Grant
    Filed: September 30, 1983
    Date of Patent: August 6, 1985
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Gunter Trummlitz, Wolfhard Engel, Ernst Seeger, Walter Haarmann
  • Patent number: 4528110
    Abstract: This invention is directed to germicidal compositions comprising a germicidally effective amount of at least one alkyl monophosphonic acid having from 4 to 12 carbon atoms in the alkyl chain in admixture with one or more surfactants in acidic solution and to the use of such compositions in disinfecting surfaces.
    Type: Grant
    Filed: June 22, 1983
    Date of Patent: July 9, 1985
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventor: Siegfried Bragulla
  • Patent number: 4528126
    Abstract: 2,4-dioxa-7,10-methano-spiro [5,5] undecanes having the formula ##STR1## wherein R is a member selected from the group consisting of hydrogen, alkyl having from 1 to 4 carbon atoms, vinyl and propenyl and their isomeric mixtures; its synthesis, its use as a perfumery agent and as an olefactant component in perfumery compositions and as an odorant for technical products.
    Type: Grant
    Filed: October 4, 1983
    Date of Patent: July 9, 1985
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Klaus Bruns, Thuy N. Dang
  • Patent number: D280571
    Type: Grant
    Filed: December 15, 1982
    Date of Patent: September 17, 1985
    Inventor: Matti Viio