Patents Represented by Attorney, Agent or Law Firm Hansjorg Sauer
  • Method for inhibiting platelet aggregation
    Patent number: 6770660
    Abstract: A method for inhibiting platelet aggregation in a patient in need thereof, comprising 1) administering to the patient a bolus injection of an active drug, in an amount of about 25 &mgr;g/kg, and 2) administering to the patient, after the bolus injection, an intravenous infusion for a period of between about 12 hours and about 72 hours, of the active drug, in an amount of about 0.15 &mgr;g/kg/min, wherein the active drug is tirofiban or a salt thereof.
    Type: Grant
    Filed: May 1, 2003
    Date of Patent: August 3, 2004
    Assignee: Artery LLC
    Inventors: Peter M. DiBattiste, David Schneider
  • Trisubstituted carbocyclic cyclophilin binding compounds and their use
    Patent number: 6656971
    Abstract: The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one or more of the said compounds. The invention further relates to the uses of these compounds and compositions for binding CyP-type proteins, inhibiting their peptidyl-prolyl isomerase activity, and for research, development, and therapeutic applications in a variety of medical disorders.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: December 2, 2003
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Yong-Qian Wu, Sergei Belyakov, Gregory S. Hamilton, David Limburg, Joseph P. Steiner, Mark Vaal, Ling Wei, Douglas Wilkinson