Patents Represented by Attorney Harold D. Steinberg
  • Patent number: 4146628
    Abstract: The invention relates to the compound 2-6-xylidide of quinuclidine-3-carboxylic acid and its pharmaceutically acceptable salts, such as the hydrochloride, which have been found to be effective antiarrhythmic agents. The invention further relates to the production of this antiarrhythmic compound which method is applicable also to the production of related compounds which, however, do not have antiarrhythmic action, e.g. the quinuclidine-2-carboxylic acid xylidides. The compounds are produced according to this method by reacting the quinuclidine carboxylic acid in anhydrous chloroform and oxalyl chloride with the dimethylaniline. The desired compound is produced in high yield with a high degree of purity.
    Type: Grant
    Filed: August 4, 1977
    Date of Patent: March 27, 1979
    Inventors: Edna Oppenheimer, Eliezer Kaplinsky, Sasson Cohen
  • Patent number: 4083985
    Abstract: Compounds of the general formula ##STR1## wherein X is selected from the group consisting of oxygen CH.sub.2 and CH radicals, and when X designates oxygen, R designates alkyl, isoalkyl, aralkyl, and substituted aryl groups and when X designates ##STR2## then R designates alkyl, phenyl or substituted phenyl group, and A--B is a single bond and when X designates >CH, and A--B is a double bond, R designates alkyl, phenyl or substituted phenyl groups and physiologically acceptable salts of these, and pharmaceutical compositions containing same as active ingredient.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: April 11, 1978
    Assignee: The Purdue Frederick Company
    Inventors: Sasson Cohen, Abraham Fisher
  • Patent number: 4067974
    Abstract: Choline salicylate is stabilized in solid form by means of a metal salicylate having a valence of at least 2, preferably aluminum, bismuth, calcium or magnesium salicylate. The composition is stabilized to a still greater degree by the addition thereto of carboxy-methyl cellulose. A still greater degree of stabilization is achieved by forming a complex of the choline salicylate, metal salicylate and carboxy-methyl cellulose. The complex is formed by preparing a solution of the carboxy-methyl cellulose, choline salicylate and metal salicylate, permitting complexng reaction to take place and drying. All of these stabilized forms of choline salicylate are used in solid dosage forms such as granules, tablets, capsules and supporitories for administration to animals and humans, in the course of choline salicylate therapy, to elevate the blood levels of salicylate ion.
    Type: Grant
    Filed: July 14, 1976
    Date of Patent: January 10, 1978
    Assignee: The Purdue Frederick Company
    Inventor: Ernest J. Sasmor
  • Patent number: 3938271
    Abstract: A firearm which has a receiver formed with an ejection port through which the cartridge case of a spent cartridge is ejected. A bolt is situated in the receiver for movement between a forward firing position and a rear retracted position, a cartridge case being ejected when the bolt is in its rear retracted position. The bolt is also supported in the receiver for rotary movement between locked and unlocked positions. A sleeve is operatively connected to and surrounds the bolt for rotating the latter between its locked and unlocked positions, this sleeve having a length substantially less than the length of the bolt and covering part of the ejection port when the bolt is in its firing position. A cover is provided to cover that part of the port which is not covered by the sleeve when the bolt is in its firing position, and this cover responds to rearward movement of the bolt from its firing to its retracted position for uncovering the ejection port.
    Type: Grant
    Filed: March 29, 1974
    Date of Patent: February 17, 1976
    Assignee: Valmet Oy
    Inventor: Timo Hyytinen
  • Patent number: D243814
    Type: Grant
    Filed: April 24, 1975
    Date of Patent: March 29, 1977
    Inventor: Jose Figueras Mitjans
  • Patent number: D247579
    Type: Grant
    Filed: March 30, 1976
    Date of Patent: March 21, 1978
    Inventor: Merrill L. Laven
  • Patent number: D249928
    Type: Grant
    Filed: July 19, 1976
    Date of Patent: October 17, 1978
    Inventor: Maximiliaan DE Nijs
  • Patent number: D250069
    Type: Grant
    Filed: August 5, 1977
    Date of Patent: October 31, 1978
    Assignee: Celluloid S.A.
    Inventor: Jean L. Wachtel
  • Patent number: D250128
    Type: Grant
    Filed: August 22, 1977
    Date of Patent: October 31, 1978
    Assignee: Kabushiki Kaisha Brethren Shoji
    Inventor: Tadashi Miyazawa
  • Patent number: D250546
    Type: Grant
    Filed: September 8, 1977
    Date of Patent: December 12, 1978
    Assignee: The Purdue Frederick Company
    Inventors: Ernest W. Pick, Joseph M. Denaro, Henry R. Goerke
  • Patent number: D250600
    Type: Grant
    Filed: September 8, 1977
    Date of Patent: December 19, 1978
    Assignee: The Purdue Frederick Company
    Inventors: Ernest W. Pick, Joseph M. Denaro, Henry R. Goerke
  • Patent number: D250601
    Type: Grant
    Filed: September 8, 1977
    Date of Patent: December 19, 1978
    Assignee: The Purdue Frederick Company
    Inventors: Ernest W. Pick, Joseph M. Denaro, Henry R. Goerke
  • Patent number: D250972
    Type: Grant
    Filed: December 10, 1976
    Date of Patent: January 30, 1979
    Inventors: Viktor P. Rodin, Petr S. Zhdanov, Jury I. Prokhorov
  • Patent number: D251213
    Type: Grant
    Filed: December 10, 1976
    Date of Patent: February 27, 1979
    Assignee: Proizvodstvenny Kombinat Khudozhestvennogo Fonda
    Inventors: Viktor P. Rodin, Petr S. Zhdanov, Jury I. Prokhorov
  • Patent number: D258155
    Type: Grant
    Filed: March 1, 1979
    Date of Patent: February 3, 1981
    Assignee: Alleghany Pharmacal Corp.
    Inventor: Larry Mathews