Patents Represented by Attorney Harris F. Gray Cary Ware & Freidenrich Brotman

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  • Assay for glycosylation deficiency disorders
    Patent number: 5432059
    Abstract: A method is provided for detecting carbohydrate-deficient glycoproteins in samples taken from subjects with metabolic disorders, such as alcohol abuse and subjects who display a syndrome of carrying abnormal levels of carbohydrate deficient glycoproteins. The method involves steps of reglycosylating with a fluorescent-conjugate deglycosylated glycoproteins in a sample of body fluid from a subject. A further step involves fluorometric detection of fluoresceinylated carbohydrates incorporated into truncated serum glycoproteins.
    Type: Grant
    Filed: April 1, 1994
    Date of Patent: July 11, 1995
    Assignee: Specialty Laboratories, Inc.
    Inventors: Pamela Bean, Jeff W. Terryberry