Patents Represented by Attorney Hedlen & Carroll, LLP

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  • Anticancer glycoside compounds
    Patent number: 7144867
    Abstract: The present invention relates to new classes of anti-cancer compounds. In particular, the present invention provides glycoside compounds as anti-cancer agent, alone, or in combination with other anti-cancer agents or therapies.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: December 5, 2006
    Assignees: Northwestern University, Coastside Bio Resources
    Inventors: Thomas E. Adrian, Peter D. Collin
  • Mini-dystrophin nucleic acid sequences
    Patent number: 6869777
    Abstract: The present invention relates to compositions and methods for expressing mini-dystrophin peptides. In particular, the present invention provides compositions comprising nucleic acid sequences that are shorter than wild-type dystrophin cDNA and that express mini-dystrophin peptides that function in a similar manner as wild-type dystrophin proteins. The present invention also provides compositions comprising mini-dystrophin peptides, and methods for expressing mini-dystrophin peptides in target cells.
    Type: Grant
    Filed: October 4, 2001
    Date of Patent: March 22, 2005
    Assignee: Regents of the University of Michigan
    Inventors: Jeffrey S. Chamberlain, Scott Q. Harper
  • Compositions and methods for the treatment of sepsis
    Patent number: 6673346
    Abstract: The present invention relates to compositions and methods for the prevention and treatment of blood-borne and toxin mediated diseases, and in particular anti-C5a antibodies for the prevention and treatment of sepsis in humans as well as other animals. The present invention also relates to methods of generating anti-C5a antibodies employing C-terminal truncated C5a peptides.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: January 6, 2004
    Assignee: The Regents of the University of Michigan
    Inventors: Peter A. Ward, Markus Huber-Lang, Vidya Sarma, Boris Czermak
  • Colorimetric glycopolythiophene biosensors
    Patent number: 6660484
    Abstract: The present invention relates to methods and compositions for the direct detection of analytes using observable spectral changes in biopolymeric systems. In particular, the present invention allows for the direct colorimetric detection of analytes using color changes that occur in glycopolythiophene polymer systems in response to selective binding of analytes.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: December 9, 2003
    Assignee: Regents of the University of California
    Inventors: Deborah J. Charych, Myung-Gi Baek
  • Inhibition of cell-cell binding by lipid assemblies
    Patent number: 6235309
    Abstract: This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides products and methods for inhibiting cell migration and activation using lipid assemblies with surface recognition elements that are specific for the receptors involved in cell migration and activation.
    Type: Grant
    Filed: February 27, 1998
    Date of Patent: May 22, 2001
    Assignee: The Regents of the University of California
    Inventors: Jon O. Nagy, Robert F. Bargatze