Patents Represented by Attorney, Agent or Law Firm Hedman & Costigen, P.C.
  • Monocyclic compounds with four bifunctional residues having NK-2 antagonist action
    Patent number: 6780968
    Abstract: Disclosed are monocyclic compounds containing four bifunctional residues linked together via peptide or pseudopeptide bonds of the general formula (I): having tachykinin receptor antagonist activity. In particular, compounds of formula I are shown to be neurokinin-2 (NK-2) antagonists useful in the treatment or prevention of disorders of the central nervous system, inflammatory diseases, asthma, or pain.
    Type: Grant
    Filed: July 12, 2000
    Date of Patent: August 24, 2004
    Assignee: Menarini Ricerche S.p.A.
    Inventors: Raffaello Giorgi, Cristina Di Bugno, Danilo Giannotti, Carlo Alberto Maggi