Abstract: A tamper-proof closure for use with a bottle having a neck, a lip, and shelf surrounding the neck and a plurality of ramp sections. The closure includes a top wall, a skirt and a plurality of tabs extending from the bottom edge of the skirt. The tabs include first and second side edges and a transverse edge. The tab is longer adjacent to one side edge than the other. The ramp sections include an upwardly sloping portion of the shelf and a cam wall extending across the shelf from the neck to the outer edge of the shelf.