Patents Represented by Attorney, Agent or Law Firm Hodgson Russ
  • Patent number: 8287178
    Abstract: The invention provides a system and method for filling a reservoir through one or a plurality of inlet nozzles to encourage mixing. The inlet nozzles include a specifically designed size reduction between the main line or branch to which the inlet nozzle is attached and the nozzle pipe itself; a specifically designed nozzle pipe length which, combined with the pressure increase provided by the size reduction, will produce the most appropriate jet flow; and a specifically designed location and orientation of the inlet nozzle within the reservoir. These parameters produce a developed turbulent jet flow which, when the inlet nozzle is positioned at the appropriate elevation and oriented in the appropriate direction(s), will direct the developed turbulent jet flow with the appropriate momentum to reach the surface of the water with initial major mixing taking place in this area. A corresponding draining system and method is also disclosed.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: October 16, 2012
    Assignee: Landmark Structures I, L.P.
    Inventor: Douglas Lamon
  • Patent number: 8280691
    Abstract: The object of the invention is to implement an arrangement that enables maximally flexible linkage of measured-value sensing systems 12 to automation devices. This object is achieved in that an arrangement for evaluating the measured values of a measured-value converter 12 is provided, which arrangement encompasses an evaluation means 13 and a connecting means 18 for linking the evaluation means 13 to the measured-value transducer 12. Connecting means 18 in turn encompasses means 14, 15, 16, 17a, b that are at least in part electrically configurable, by means of parameters, in such a way that a linkage of evaluation means 13 to measured-value converters 12 that differ in terms of measured-value data transfer can be implemented.
    Type: Grant
    Filed: July 22, 2009
    Date of Patent: October 2, 2012
    Assignee: Robert Bosch GmbH
    Inventor: Gerhard Bund
  • Patent number: 8278072
    Abstract: A method for producing sialylated molecules based on reverse sialylation that catalytically transfers the sialic acid moiety of sialylated donors to nucleotide monophosphates or transfer sialic acid moieties from sialylated donors to acceptor glycoproteins or glycolipids.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: October 2, 2012
    Assignees: Health Research, Inc., The Research Foundation of State University of New York
    Inventors: Khushi L. Matta, Edaya V. Chandrasekaran, Sriram Neelamegham, Jun Xue
  • Patent number: 8277730
    Abstract: A tissue infiltration apparatus (1) for specimens present in cassettes (5) comprises at least two liquid containers (7, 11, 13, 15) and a transport apparatus (6). Multiple cassettes (5) are receivable in a transport basket (4). The transport apparatus (6) is configured in such a way that at least two transport baskets (4) are transportable in the tissue infiltration apparatus (1). A transport basket (4) is deliverable to, and/or movable away from, a liquid container (7, 11, 13, 15) with the transport apparatus (6). An execution sequence (21) in which the transport baskets (4) pass through the liquid containers (7, 11, 13, 15) is definable. To enable accelerated or preferred processing of a transport basket (4) with the tissue infiltration apparatus (1), at least one means (8) is provided with which the order of two transport baskets (4) is definably modifiable.
    Type: Grant
    Filed: October 12, 2011
    Date of Patent: October 2, 2012
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Hermann Ulbrich, Karl-Heinz Westerhoff, Stefan Künkel, Janet Minshew
  • Patent number: 8276747
    Abstract: A modular conveying system with sprockets engaging the modules such that they do not cover any link gaps but are positioned between the link gaps. The module is characterized by link structures having link pairs that are spaced apart sufficiently at a distance to allow the sprockets to be located between the link pairs. Positioning the sprockets between the link pairs leaves the hinge gaps uncovered and thus allows free access to the hinge gap for cleaning.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: October 2, 2012
    Assignee: Habasit AG
    Inventors: Dieter Guldenfels, Marco Lucchi
  • Patent number: 8257054
    Abstract: A peristaltic pump assembly includes a pump body including a mounting pin coupled thereto. A removable cassette is slidably received on the mounting pin and is secured to the pump body via a retaining feature. The mounting pin is also configured to allow the removable cassette to rotate into and/or out of an installed position, or to position(s) therebetween.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: September 4, 2012
    Assignee: Curlin Medical Inc.
    Inventors: Robert R. Voltenburg, Jr., Loren M. Thompson
  • Patent number: 8257737
    Abstract: The invention provides biocompatible, biodegradable calcium sulfate matrices containing calcium sulfate activated platelets for use in tissue formation. The matrices are particularly useful in stimulating hard tissue, for example, bone formation. The matrices may also further include a growth factor and/or a transfectable gene, the inclusion of which may be useful in stimulating the growth of tissue of interest.
    Type: Grant
    Filed: August 9, 2002
    Date of Patent: September 4, 2012
    Inventors: Giuseppe Intini, Sebastiano Andreana, Rosemary Dziak, Libuse Anna Bobek
  • Patent number: 8260623
    Abstract: Flour may be treated to denature the proteins and modify starches. The invention includes methods and systems for determining whether to use treated flour or untreated flour. The invention also includes methods and systems for determining whether to treat flour or not.
    Type: Grant
    Filed: May 4, 2009
    Date of Patent: September 4, 2012
    Assignee: Rich Products Corporation
    Inventors: Praveen Upreti, Rohit Jalali, William E. Grieshober, Jr., John S. Roberts, Melissa D. Haller, Michael Fuchs, Ilya Y. Ilyin
  • Patent number: 8257622
    Abstract: The invention proposes a muffle with a pressing channel and at least one mold cavity that is coupled to the pressing channel via at least one connection channel. In this case, in order to increase the pressing pressure and to improve the intermixing of the blank material, it is proposed to arrange at least two blanks (18) side by side in the pressing channel (12).
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: September 4, 2012
    Assignee: Ivoclar Vivadent AG
    Inventors: Harald Gritsch, Max Wörishofer, Christoph Zobler, Thomas Stampfer, Hans-Peter Foser
  • Patent number: 8256332
    Abstract: A method for the automatic and contact-free relative approach between a specimen (6) and a knife (7) of a microtome (1). A first light beam bundle (9?) forms a detector-side zero point and a last light beam bundle (9?) forms a detector-side end point of a light band (8), the light band (8) being arranged perpendicular to the second spatial direction (Y) and in the direction thereof spaced from the knife, a zero point (X0) being assigned to a reference position of the knife blade (XBlade). The specimen (6) is guided through the light band (8) by way of a cutting movement. The position of the highest point of the specimen (XSpecimen) in the first spatial direction (X) is determined from the number of shaded light beam bundles (9).
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: September 4, 2012
    Assignee: Leica Biosystems Nussloch GmbH
    Inventor: Roland Walter
  • Patent number: 8254137
    Abstract: An electronic device for use in a health care setting has a rigid enclosure assembly formed by a rigid shell and a rigid printed circuit board carrying circuitry for operating the device. A switch dome layer and an overlay are independently attached to the device but not to each other, whereby the overlay may be removed without disturbing the dome layer and a better tactile response is achieved.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: August 28, 2012
    Assignee: Curbell Medical Products, Inc.
    Inventors: Edward A. Wilkolaski, Abhilash J. Prasad, Edgar P. Conrad, John Waterhouse, Larry Hall, Arthur P. Caprio, Christopher P. Camacho
  • Patent number: 8252527
    Abstract: Provided are methods for identifying a polynucleotide that can reduce the level of a target mRNA. The method can be performed by providing cells that express an RNA polynucleotide that contains a target mRNA sequence, an internal ribosome entry sequence (IRES) and a sequence encoding a secreted reporter protein; introducing to the cells a test polynucleotide, and measuring activity of the secreted reporter protein. A reduction in secreted reporter protein activity relative to a control cell into which the test polynucleotide has not been introduced is indicative that the test polynucleotide is capable of reducing the level of the target mRNA in the cells. The method is adaptable for high throughput screening methods and is suited for identifying polynucleotides that can catalyze cleavage of target mRNA and/or act on target mRNA through and antisense or RNAi mechanism.
    Type: Grant
    Filed: February 19, 2008
    Date of Patent: August 28, 2012
    Assignee: The Research Foundation of State University of New York
    Inventors: John M. Sullivan, Edwin H. Yau
  • Patent number: 8252358
    Abstract: The present invention provides a substantially protein-free whippable food product having improved stability characteristics without detectable change in the organoleptic characteristics. The product comprises triglyceride fat, one or more sugars, an emulsifier component, a starch component comprising one or more NOSA starches and one or more hydrophilic starches, and optionally an acid component. This product can be stored frozen or at ambient temperatures for extended periods of time and can also be whipped and displayed at ambient temperatures.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: August 28, 2012
    Assignee: Rich Products Corporation
    Inventors: Michael Piatko, Cheryl Perks
  • Patent number: 8247013
    Abstract: The present invention provides a method for producing frozen dough which can be directly transferred from freezer to oven without a proofing or thawing step. The process comprises mixing the dough ingredients, forming gas nucleation sites, exercising the dough by subjecting to cycles of pressure differentials and freezing the dough. The frozen product can be transferred directly from the freezer to an oven for baking.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: August 21, 2012
    Assignee: Rich Products Corporation
    Inventors: Praveen Upreti, Rohit Jalali, Melissa Haller, Nikolay Shkolnik, Pavel Yurievich Koblents, Dmitry Ivanovich Pivunov
  • Patent number: 8241503
    Abstract: Disclosed is an economical process for the purification of water containing soluble and sparingly soluble inorganic compounds using single-stage or two-stage membrane processes that integrate membrane water purification with chemical precipitation softening and residual hardness and silica removal from the membrane concentrates using ion exchange resins and silica sequestering media, respectively.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: August 14, 2012
    Inventor: Riad Al-Samadi
  • Patent number: 8241845
    Abstract: The invention provides an isolated, novel steroid 5?-reductase enzyme termed SRD5AIII. The protein has an estimated molecular weight of 37 kDa and is capable of converting testosterone to dihydrotestosterone at a pH of about 7.0. Also provided is a method for identifying inhibitors of SRD5AIII by contacting SRD5AIII with a test compound and measuring the activity of the enzyme. A reduced activity relative to a control indicates that the test compound is an inhibitor of SRD5AIII. A method is also provided for detecting androgen stimulated prostate cancer or recurrent prostate cancer in an individual. The method comprises obtaining a prostate biopsy from an individual and determining the level of expression of SRD5AIII gene or protein relative to a normal control. An increased expression of SRD5AIII relative to the control is indicative of androgen stimulated prostate cancer or recurrent prostate cancer.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: August 14, 2012
    Assignee: Health Research Inc.
    Inventors: James L. Mohler, Mark Titus, Olga Kozyreva, O. Harris Ford, III, Elsbieta Kawinski, Yun Li
  • Patent number: 8235828
    Abstract: A diaphragm coupling having first and second diaphragm plates that are joined together around their outer edges. Each diaphragm plate has a central, axially-extending hub. The hub of the first plate supports within it a pin member having an outwardly projecting shoulder at each end adapted to engage an internal shoulder on the hub of the first plate at one end and an internal shoulder on the hub of the second plate at the other end so as to limit axial separation of the two hubs—from one another.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: August 7, 2012
    Assignee: Moog Wolverhampton Limited
    Inventors: Jonathan Paul Davies, Tony Wilson
  • Patent number: 8236320
    Abstract: Provided are methods for stimulating an immune response to an antigen by administering a composition to an individual in an amount effective to stimulate an immune response to the antigen. The stimulated immune response to the antigen is greater than the immune response stimulated by the antigen in the absence of CA9 protein. The compositions provided contain a complex that includes an antigen and an isolated CA9 protein.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: August 7, 2012
    Assignee: Health Research Inc.
    Inventors: Hyung L. Kim, Yanping Wang, Xiang-Yang Wang, John R. Subjeck
  • Patent number: 8232506
    Abstract: The present invention relates to a dental firing furnace having a firing space and at least one carrier for dental material, in particular a muffle, which can be loaded into the firing space, and, in particular, a pressing device for pressing a ceramic blank inserted in the muffle, at least one physical variable of the firing space and/or of the carrier and/or of the muffle and/or of the ceramic blank being detected. A processing program of the dental furnace (10) that can be set is based on the detected physical variable.
    Type: Grant
    Filed: March 30, 2008
    Date of Patent: July 31, 2012
    Assignee: Ivoclar Vivadent AG
    Inventor: Rudolf Jussel
  • Patent number: 8232433
    Abstract: The present invention is intended to provide a catalyst which is for synthesizing butanol from ethanol at a high selectivity and which comprises strontium phosphate apatite having the Sr/P atomic ratio of 1.5-2.0, and the synthesis method.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: July 31, 2012
    Assignees: Kabushiki Kaisha Sangi, Kochi University
    Inventors: Ayumu Onda, Shuhei Ogo, Kazumichi Yanagisawa