Abstract: A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets. After the biocompatible tissue material is folded, it is affixed at one or more points on the outer surface to the inner cavity or a stent.

Abstract: A cotton cultivar, designated L-1000, is disclosed. The invention relates to the seeds of cotton cultivar L-1000, to the plants of cotton L-1000 and to methods for producing a cotton plant produced by crossing the cultivar L-1000 with itself or another cotton variety. The invention further relates to hybrid cotton seeds and plants produced by crossing the cultivar L-1000 with another cotton cultivar.

Abstract: A cotton cultivar, designated L-9009-6, is disclosed. The invention relates to the seeds of cotton cultivar L-9009-6, to the plants of cotton L-9009-6 and to methods for producing a cotton plant produced by crossing the cultivar L-9009-6 with itself or another cotton variety. The invention further relates to hybrid cotton seeds and plants produced by crossing the cultivar L-9009-6 with another cotton cultivar.

Abstract: Disclosed herein are a Pichia pastoris-derived auto-inducible NPS promoter; a recombinant expression vector carrying the promoter and a nucleotide sequence, the sequence being operably linked to the promoter and coding for a recombinant protein; a host cell transformed or transfected with the recombinant expression vector; and a method for producing a recombinant protein, comprising culturing the host cell to express the recombinant protein and isolating the protein. The NPS promoter allows a recombinant protein of interest to be produced on a large scale without the need of any inducer.

Abstract: The present invention relates to a transcriptional regulatory sequence with enhanced tumor-specificity and strength and a recombinant vector comprising the transcriptional regulatory sequence. More particularly, the present invention relates to a transcriptional regulatory sequence comprising a human telomere reverse transcriptase (hTERT) promoter linked to a nucleotide sequence that comprises one or more c-Myc binding sites and/or one or more Sp1 binding sites, and a recombinant vector comprising a certain gene that is operably linked to the above transcriptional regulatory sequence.

Abstract: This invention relates, in general, to a method of producing magnetic oxide nanoparticles or metal oxide nanoparticles and, more particularly, to a method of producing magnetic or metal oxide nanoparticles, which comprises (1) adding a magnetic or metal precursor to a surfactant or a solvent containing the surfactant to produce a mixed solution, (2) heating the mixed solution to 50-6001 C to decompose the magnetic or metal precursor by heating so as to form the magnetic or metal oxide nanoparticles, and (3) separating the magnetic or metal oxide nanoparticles. Since the method is achieved through a simple process without using an oxidizing agent or a reducing agent, it is possible to simply mass-produce uniform magnetic or metal oxide nanoparticles having desired sizes compared to the conventional method.

Abstract: The present invention relates to a neural device comprising wires transmitting and receiving electric signals. More specifically, the present invention relates to a structure of the neural device comprising wires which effectively obtain electric signals developed in nerve fibers and transmit electric stimuli to the nerve fibers. The neural device according to the present invention is connected to a processing module processing electric signals detected from nerve fibers, and the neural device is inserted in nerve fibers via nanowires to obtain electric signals from the nerve fibers, or inserted in the nerve fibers to transmit electric stimuli. The neural device may further provide with at least one through-hole and support. The neural device according to the present invention has an advantage that may obtain electric signals without killing nerve fibers or provide them with electric stimuli.

Abstract: A training tourniquet for use in training a user or another person, such as a medic, includes a non-functioning tensioning mechanism to model application of developing a tensile force in a strap of a tourniquet. The training tourniquet has particular application to training field personnel, such as medics and soldiers as to how to apply a tourniquet, without actually creating a compressive force that could damage a person's tissue during the training or practice sessions. In one embodiment, an inoperative windlass can be rotated to simulate the action necessary to create tension in a strap of a real tourniquet, however, the inoperative windlass spins around without actually tightening a strap of the training tourniquet.

Abstract: A rod extension for extending a fusion construct allows a surgeon to connect a stabilization rod implant to at least a portion of a patient's spine, and also to connect the stabilization rod implant to an existing implant that has been previously installed in the patient. The existing fusion implant typically includes at least one existing pedicle screw, at least one existing rod, and at least one existing connector interconnecting the existing pedicle screw to the existing rod. The extension implant comprises a rod, an offset beam connected to the rod, and a clamp interconnected to the offset beam, wherein the clamp can be secured to the existing rod, thereby extending the fusion construct.

Abstract: A drill bit assembly comprises a bit body intermediate a shank and a working face. The shank is adapted for connection to a drill string. The drill string comprising a fluid passage at least partially disposed within the body. A hammer assembly is movably disposed within the fluid passage along it central axis, the hammer assembly comprises a proximal end stabilized by a centralized upper bearing and a distal end stabilized by centralized a lower bearing. The distal end protrudes out of the working face and the hammer assembly comprises a carrier between the upper and lower bearings. Wherein, under normal drilling operations the carrier is adapted to resist a fluid pressure within the fluid passageway such that the fluid pressure will further extend the distal end of the hammer assembly from the working face by pushing on the carrier.

Abstract: In one aspect of the invention, a pick comprises a carbide bolster disposed intermediate an impact tip and a shank assembly. The impact tip comprises a superhard material bonded to a carbide substrate, and the tip is bonded to the bolster opposing a base of the bolster. The shank assembly comprises a central axis, a first end that protrudes into a cavity formed in the base of the bolster, and also an inducible attachment mechanism disposed proximate the first end. The inducible attachment mechanism is adapted to attach the shank assembly to the carbide bolster and restrict movement of the shank assembly with respect to the carbide bolster. The attachment mechanism may restrict movement of the shank assembly in a direction parallel to the central axis.

Abstract: Produced natural gas containing carbon dioxide is dehydrated and chilled to liquefy the carbon dioxide and then fractionated to produce a waste stream of liquid carbon dioxide and hydrogen sulfide. Natural gas liquids may be first separated and removed before fractionation. After fractionation, the waste stream is pressurized and transmitted to a remote injection well for injection either for disposal of the waste stream and preferably to urge hydrocarbons toward the producing well. A hydrocarbon stream proceeds from fractionation to a methanol absorber system which removes carbon dioxide gas. The hydrocarbon stream is thereafter separated into at least hydrocarbon gas, nitrogen and helium. Some of the nitrogen is reintroduced into a fractionation tower to enhance the recovery of hydrocarbons. A methanol recovery system is provided to recover and reuse the methanol. The hydrocarbons are sold as natural gas and the helium is recovered and sold. Excess nitrogen is vented.

Abstract: In one aspect of the present invention, a high impact resistant excavation pick having a super hard material is bonded to a cemented metal carbide substrate at a non-planar interface. The cemented metal carbide substrate is bonded to a front end of a cemented metal carbide frustum. A tapered bore is formed in the base end of the carbide frustum opposite the front end and a steel shank with a tapered interface is fitted into the tapered bore.

Abstract: Apparatus and methods for amplification of DNA are provided that use sonic energy in place of conventional thermocyclers. In one embodiment, sonic energy is applied to a PCR cocktail to effect dissociation of double stranded DNA into single strands of DNA. A quiescence stage, where no sonic energy is applied, results in amplification of DNA. Repetition of the cycles of application of sonic energy and cessation of application of sonic energy results in DNA amplification.

Abstract: A degradation assembly comprises a rotary portion and a stationary portion. The rotary portion includes a cemented metal bolster bonded to a tip. The tip comprises a asymmetric, substantially conically shaped tip formed of diamond and a cemented metal carbide substrate. The stationary portion comprises a holder configured to be coupled to a block mounted to a driving mechanism. A compressible element is disposed between and in mechanical contact with both the rotary portion and the stationary portion.

Abstract: A frame is formed of side walls that are extruded from vinyl. The side walls have interior channels. The side walls may be formed to effect a female-male connection between the ends of two adjoining side walls. Alternatively a locking member is provided that is sized to frictionally engage a selected channel. The side walls have a concrete retention fin positioned to extend away from the outer wall of the side wall to interconnect with the concrete as the and after the concrete cures. The frame may be formed into door jambs, doors, and the like. The frame may also be a window buck that may be formed into selected geometric shapes. Window bucks of different dimensions may be assembled on site by sawing.