Abstract: Aqueous solutions of certain cationic (meth)acrylic ester copolymers can be used to coat dosage forms to taste- and odor-mask bio-active agents therein. Pellets are highly preferred dosage forms.
Type:
Grant
Filed:
May 30, 1986
Date of Patent:
November 22, 1988
Assignee:
Warner-Lambert Company
Inventors:
Isaac Ghebre-Sellassie, Robert Gordon, Maryann Mench, Russell U. Nesbitt, Jr., Mary E. Trapold
Abstract: A process and composition for inhibiting surfactant irritation and insult comprising an aqueous solution of a surfactant and an effective amount of an irritation inhibitor selected from the group consisting of lecithin, sodium cetearyl sulfate, an amino acid, cocamine compounds, amine oxides, glyceryl monoesters, ethoxylated monocarboxylic acids, ethoxylated hydroxyl compounds and mixtures thereof.
Abstract: A lubricating strip having a honeycomb structure of polystyrene and a water soluble leachable shaving aid of high molecular weight polyethylene oxide is molded in situ on a razor cap made of thermoplastic material which has been previously injection molded.
Type:
Grant
Filed:
January 16, 1987
Date of Patent:
October 18, 1988
Assignee:
Warner-Lambert Company
Inventors:
David B. Braun, William E. Vreeland, Vincent C. Motta
Abstract: According to this invention a blade assembly is created featuring pivotally mounted first and second blades with pivot and subsequent change the span of each blade in response to the amount of shaving force generated by the user.
Abstract: A capsule sealing machine (10) in which capsules (C) are fed from a supply hopper (16) to a rotating sealing table (12) for banding or sealing the capsules as they pass over a set of sealing wheels (13). The sealing machine has an improved capsule guide (22) for feeding the capsules from the hopper to the table, thereby reducing the cost and complexity of the machine while at the same time enabling a greater number of capsules to be sealed or banded in a given amount of time and space. The capsule guide comprises slotted magazine sections (23, 28 and 30) which are caused to vibrate by a vibrator (48) to promote discharge of capsules from the hopper and to advance the capsules along the slots. In one form of the invention, a capsule orienting device (51) is disposed in alignment with the magazine to orient the capsules in a desired end-for-end relationship before they are discharged onto the table.
Abstract: A method for sealing capsules which comprises contacting the cap and body juncture with a sealing solution of alcohol and water maintained between about 40.degree. C. to the boiling point of the fluid. A secondary gelatin band seal is also contemplated in one aspect of the invention, as well as a capsule having both seals.
Type:
Grant
Filed:
July 25, 1986
Date of Patent:
July 12, 1988
Assignee:
Warner-Lambert Company
Inventors:
Larry L. Harvey, Bakul T. Doshi, Edward W. Sunbery
Abstract: This invention provides a razor having a knurled guard bar and a single sharp blade particularly adopted for shaving one suffering from pseudofolliculitis barbae.
Abstract: Novel injection molded pharmaceutical capsules of starch having a cap member, a body member, means to form a plurality of compartments therein; and means for locking the cap and body members together to form a tamper-resistant connection.
Type:
Grant
Filed:
September 19, 1986
Date of Patent:
April 19, 1988
Assignee:
Warner-Lambert Company
Inventors:
Fritz Wittwer, Ivan Tomka, Hans-Ulrich Bodenmann, Thomas Raible, Louis S. Gillow
Abstract: Novel injection molded pharmaceutical capsules of gelatin having a cap member, a body member, means to form a plurality of compartments therein, and means for locking the cap and body members together to form a tamper-resistant connection.
Type:
Grant
Filed:
September 19, 1986
Date of Patent:
April 19, 1988
Assignee:
Warner-Lambert Company
Inventors:
Fritz Wittwer, Ivan Tomka, Hans-Ulrich Bodenmann, Thomas Raible, Louis S. Gillow
Abstract: Improved apparatus for heat-treating gelatin capsules containing a medicament to cause heat-seal of the telescoped cap and body wall portions thereof, the apparatus comprising a housing defining an elongate generally cylindrical passageway sloping downwardly from inlet to outlet for receiving and discharging capsules passing therethrough, a capsule conveyor comprising an elongate rotatable shaft mounted on the longitudinal cylindrical axis of the passageway for rotation and carrying a plurality of generally circular conveyor plates, each plate supportably mounted in spaced relation along the shaft and having extending ramp portions communicating with the top surface of the next adjacent plate in the direction of the housing passageway outlet to define a generally Archimedean screw-shaped path for passage of gelatin capsules through the housing passageway from inlet to outlet, air-distributing means comprising an elongate manifold attached to the housing having a first section communicating with the passageway
Abstract: Improved method and apparatus for use in sealing gelatin capsules filled with medicinal ingredients wherein each capsule has a generally cylindrical cap and body arranged with the side wall of the body telescopically within the side wall of the cap to contain the medicament therein comprising an economical and compact wetting device for automatically conveying filled capsules from a capsule-filling machine by pneumatic pressure conveyance through one or more passageways to a wetting location where each capsule is maintained in a generally cap-upright position and metered amounts of a wetting liquid are applied to side wall portions of the body of the capsule adjacent the seam of the cap and body to pass by capillary action into the space between the overlapping cap and body side walls, and the capsules are released from wetting positions in the passageways for further pneumatic conveyance to a point of heat treatment for final sealing of the body and cap portions of the capsule to prevent their separation and
Abstract: According to this invention a razor pack adapted to hold a plurality of razors of substantially identical configuration has a plastic sleeve, which is formed to cover aligned razor heads, the sides of the heads, and a portion of the bottom of the razor. The individual razor units are inserted in the sleeve and the sleeve is attached to a card having a raised rear portion forming an abutment for the back of the sleeve and a closed front portion forming a stop for the razor handles.
Abstract: Foam capsules with telescopically engaged body and cap portions, also known as hard shell capsules, having a special wall structure, obtained by a microdispersion of a gas in a gelatin solution.The capsule body and cap portions are formed by dipmolding the film-forming mixture obtained by a microdispersion of the gas in a gelatin solution; optionally with the inclusion of a plasticizer and/or coloring agent, and/or flavoring agent, and/or foam stabilizer, and/or gelatin extender.By a suitable choice of the gas proportion in the capsule wall and its micronization level, it is possible, within certain limits, to control the capsule wall disintegration speed and its opacity. In addition, inclusion of gas bubbles into the capsule wall lowers the gelatin content for a foam capsule and provides energy saving during the process due to a faster drying of the wall, thereby providing lower cost prices for the production of pharmaceutically acceptable capsules.
Abstract: A test reagent system and method for detecting the presence of peroxidase-like activity is provided by the present invention. The reagent system comprises a free-flowing granular indicator material comprising a granular substrate such as sorbitol or mannitol having coated thereon gum guaiac and an aqueous organic reagent solution containing water, an organic solvent, an oxidizing agent being capable of oxidizing the indicator material in the presence of peroxidase-like activity, and a buffer.
Type:
Grant
Filed:
December 20, 1985
Date of Patent:
January 12, 1988
Assignee:
Warner-Lambert Company
Inventors:
Alexander M. Schobel, Raymond L. Mohrle
Abstract: According to this invention a blade assembly is created featuring pivotally mounted first and second blades with pivot and subsequent change the span of each blade in response to the amount of shaving force generated by the user.
Abstract: This invention relates to a razor blade assembly and particularly to a cap for blade assembly in which a rectangular shaving aid has been attached by means of deformable positioning means extending upward from the cap.
Abstract: Anhydrous emulsion with an oil phase (o) and a hydrophilic phase (p) of water-soluble, but anhydrous liquids, particularly as a filler matrix for medicinal preparations in capsules, which on the one hand does not attack the capsule wall and on the other permits an excellent active agent release.
Abstract: According to this invention, a pivotally mounted cartridge is provided having pivotal attachment means at or near either end of the cartridge and arcuate cam means which replace the V-shaped cam to provide a pivoting razor wherein the biasing forces are essentially even throughout the arc of the pivot. The balancing of biasing forces result in maintaining the cartridge orientation relative to the face after the initial orientation has been established.