Abstract: This invention relates to an electrophoretic display or a liquid crystal display and novel processes for its manufacture. The electrophoretic display (EPD) of the present invention comprises microcups of well-defined shape, size and aspect ratio and the microcups are filled with charged pigment particles dispersed in an optically contrasting dielectric solvent. The liquid crystal display (LCD) of this invention comprises well-defined microcups filled with at least a liquid crystal composition having its ordinary refractive index matched to that of the isotropic cup material. A novel roll-to-roll process and apparatus of the invention permits the display manufacture to be carried out continuously by a synchronized photo-lithographic process.

Abstract: A device for automatically milking an animal, which device is provided with a milking robot, a computer for controlling the operation of the device, a measuring device for performing measurements on milk obtained from an animal, at least two teat cups, and a common milk line for discharging milk coming from the at least two teat cups, each teat cup being connected via a teat cup line to the common milk line. The device is provided with a milk-determining element for determining the teat cup from which comes the milk present in the common milk line and for emitting a determination signal. The measuring device comprises a common sensor for performing measurements on milk obtained from an animal and for emitting a measurement signal. The common sensor is disposed in the common milk line. The computer is suitable for combining the measurement signal and the determination signal.

Abstract: The present invention is directed to P1, P4-di(uridine 5?)-tetraphosphate, tetra-alkali metal salts such as tetrasodium, tetralithium, tetrapotassium, and mixed tetra-alkali metal cations thereof. The tetra alkali metal salts of P1, P4-di(uridine 5?)-tetraphosphate are water-soluble, nontoxic, and easy to handle during manufacture. These tetra-monovalent alkali metal salts are more resistant to hydrolysis than the mono-, di-, or tri-acid salts, therefore, they provide an improved stability and a longer shelf life for storage. The present invention also provides methods for the synthesis of P1, P4-di(uridine 5?)-tetraphosphate, and its pharmaceutically acceptably acceptable salts thereof, and demonstrates the applicability to the production of large quantities. The methods substantially reduce the time required to synthesize diuridine tetraphosphate, for example, to three days or less.

Abstract: This invention relates to an electrophoretic display comprising cells of well-defined shape, size and aspect ratio which cells are filled with charged pigment particles dispersed in a solvent, and novel processes for its manufacture.

Abstract: A wireless system comprises at least one subscriber unit in wireless communication with an infrastructure. Each subscriber unit implements a speech recognition client, and the infrastructure comprises a speech recognition server. A given subscriber unit takes as input an unencoded speech signal that is subsequently parameterized by the speech recognition client. The parameterized speech is then provided to the speech recognition server that, in turn, performs speech recognition analysis on the parameterized speech. Information signals, based in part upon any recognized utterances identified by the speech recognition analysis, are subsequently provided to the subscriber unit. The information signals may be used to control the subscriber unit itself; to control one or more devices coupled to the subscriber unit, or may be operated upon by the subscriber unit or devices coupled thereto.

Abstract: This invention relates to an electrophoretic display comprising cells of well-defined shape, size and aspect ratio which cells are filled with charged pigment particles dispersed in a solvent, and novel processes for its manufacture.

Abstract: The present invention provides a method of preventing or treating retinal degeneration arising from pathophysiological or physical conditions. The method comprises administering to a patient a pharmaceutical composition comprising a purinergic P2Y receptor ligand, in an amount effective to elevate its extracellular concentration to activate retinal glial and neuronal cell surface P2Y receptors and mount a neuroprotective response. Methods of administering including intravitreal bolus and sustained administrations, transscleral delivery, topical, and systemic administrations. The pharmaceutical composition useful in this invention comprises a P2Y purinergic receptor agonist, which include uridine 5?-di-and triphosphate (UDP, UTP) and their analogs, adenosine 5?-diphosphate (ADP) and its analogs, cytidine 5?-di-and triphosphate (CDP, CTP) and their analogs, and dinucleoside polyphosphate compounds.

Abstract: Polymers and copolymers synthesized by means that yield a narrow range of molecular weights can have different properties than polymers synthesized by conventional means. In order to obtain such polymers, however, polymerization must be controlled. One type of controlled polymerization is the reversible addition-fragmentation chain transfer (RAFT) process, which has characteristics of a living polymerization. The present invention discloses a group of dithioesters and trithioesters suitable as chain transfer agents for RAFT polymerization. The present invention also discloses RAFT polymerizations conducted in aqueous media.

Abstract: The present invention is directed to a display device which includes an array of sealed microcups containing particles of a designated electric and magnetic characteristic suspended in a solvent wherein a surface of a plurality of the sealed microcups constituting a transparent surface. The display device further includes an electromagnetic image writing/drawing pen for manually applying an electromagnetic field on the particles of the designated electric and magnetic characteristic in the microcups to form an image viewable from the transparent surface. More particularly, the particles of the designated electric and magnetic characteristic are charged particles and the writing and drawing pen is an electrical writing/drawing pen.

Abstract: This application is directed to electrophoretic displays and semi-finished display panels comprising display cells prepared from the microcup and top-sealing technologies.

Abstract: The present invention provides a method of treating edematous retinal disorders. The method comprises administration of a pharmaceutical formulation comprising a hydrolysis-resistant P2Y receptor agonist to stimulate the removal of pathological extraneous fluid from the subretinal and retinal spaces and thereby reduce the accumulation of said fluid associated with retinal detachment and retinal edema. The P2Y receptor agonist can be administered with therapeutic and adjuvant agents commonly used to treat edematous retinal disorders. The pharmaceutical formulation useful in this invention comprises a P2Y receptor agonist with enhanced resistance to extracellular hydrolysis, such as dinucleoside polyphosphate compounds, or hydrolysis-resistant mononucleoside triphosphates.

Abstract: Compounds of formula 1 modulate the activity of Rho C: wherein R1 is H, OH, or lower alkyl; R2, R3, R4, R5, and R6 are each independently H, halo, lower alkyl, OH, lower alkoxy, NH2, lower alkylamino, di(lower alkyl)amino, SH, lower alkylthio, NO2, or two residues together form a heterocyclic ring; R7, R8, R9, and R10 are each independently H, lower alkyl, OH, NH2, aryl, or aralkyl, where aryl and aralkyl are substituted with 0-3 moieties selected from the group consisting of halo, OH, NH2, lower alkyl, lower alkoxy, SH, lower alkylthio, and lower alkylamino; R11, R12, R13, R14, R15, and R16 are each independently H, halo, lower alkyl, OH, lower alkoxy, or NO2; or a pharmaceutically acceptable salt thereof.

Abstract: A device for automatically milking an animal. The device is provided with at least two teat cups to be connected to respective teats of the animal. The milking vacuum unit generates a milking vacuum in the teat cups, which milking vacuum unit comprises at least two vacuum lines that are each connectable to a respective teat cup. The milking vacuum unit comprises a common vacuum pump and a common buffer vessel to which vacuum can be applied by use of the common vacuum pump. All vacuum lines are connectable to the common buffer vessel. An individual buffer vessel is provided in each vacuum line and is disposed between the common buffer vessel and the respective teat cup. An individual buffer vessel is provided with a respective individual vacuum pump for applying vacuum to the individual buffer vessel.

Abstract: A method for power optimization in a vehicle/train, using time reserves which are included when planning a schedule, is proposed. In order to achieve a power-saving travel mode with the aid of an optimization algorithm, the presence of a number of completely or partially autonomous drive systems is taken into account, the separate functions of efficiency or power loss of each drive system being taken into consideration.

Abstract: A dietary supplement for mammalian consumption, and particularly human consumption, for the purpose of stimulating the immune system, inhibiting infection and increasing tissue repair and healing. Comprising colostrum, lactoferrin, and with modified citrus pectin as an optional component, the dietary supplement is administered in ‘mucosal delivery format’: a dosage form that promotes effective absorption through the lining of the oral cavity.

Abstract: A well fracturing fluid comprising one or more anionic viscoelastic surfactants and one or more polymers is described. The fluids can contain an aqueous or non-aqueous fluid and/or buffer for adjusting the pH of the fracturing fluid. The well service fluid can used as a fracturing fluid in order to control water production from a well, while simultaneously increasing the oil production from the well.

Abstract: A threaded pipe connection having box and pin members is provided with inner engageable thread means on the box and pin members, the thread means including a helical dove-tail thread having negative flank angles extending along the lengths of the box and pin members, and a helical intermediate thread having positive flank angles extending along the lengths of the box and pin members adjacent the dove-tail thread. Upon makeup, the intermediate threads generate hoop tension in the box member and hoop compression in the pin member, and the dove-tail threads generate hoop compression in the box member and hoop tension in the pin member.

Abstract: A dictation system is formed of two personal computers connected by an e-mail system. A hand microphone with control switches is provided at one personal computer and a foot pedal is provided at the other personal computer. The hand microphone is used to generate a dictation file at the first personal computer. In response to actuation of a control switch on the hand microphone, the dictation file is transmitted via the electronic mail system to the second personal computer. The foot pedal at the second personal computer is used to control audible reproduction of the dictation file for the purpose of transcription at the second personal computer. The resulting text file is sent via the electronic mail system from the second personal computer to the first personal computer.

Abstract: A tapping connector for a pipeline, vessel or the like wherein the connector has a membrane disposed therein. The membrane may be curved or arcuate and may be configured to offer a partially cylindrical profile that resembles the wall of a pipe. The tapping connector may be used to provide future connection points for branch lines to the pipeline, vessel or other containment structure. The membrane so configured may be removed by conventional pipe tapping equipment.

Abstract: The present invention relates to a liquefaction reactor with three distinct elements. First, an anchor type mixer with vertical blades near the reactor wall is used to prevent accumulation of viscous materials near the reactor wall. Second, the center shaft of the anchor mixer doubles as an auger mixer to provide vertical mixing and to draw any floating, unmelted waste below the surface. Finally, a dead zone nozzle at the bottom of the reactor is used to accumulate inorganic, undissolved solids and facilitate removal of these solids.