Abstract: Alicyclic imidazole compounds; pharmaceutically active compositions containing such compounds; and the use of such compounds in formulations for the control or prevention of disease states in which histamine H3 receptors are involved, such as allergy, inflammation, hypotension, glaucoma, sleeping disorders, states of hyper- and hypo-motility of the gastro-intestinal tract, cardiovascular disease, hypo- and hyper-activity of the central nervous system, Alzheimer's, schizophrenia, obesity and migraines are disclosed.
Type:
Grant
Filed:
August 4, 2003
Date of Patent:
September 21, 2004
Assignee:
Merck & Co., Inc.
Inventors:
Yajing Rong, Jack B. Jiang, Syed M. Ali