Patents Represented by Attorney I.P. Group; Myrexis, Inc.

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  • Pharmaceutical compounds as activators of caspases and inducers of apoptosis and the use thereof
    Patent number: 7842805
    Abstract: Disclosed are 1-arylamino-phthalazines, 4-arylamino-benzo[d][1,2,3]triazines, and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: November 30, 2010
    Assignees: Myrexis, Inc., EpiCept Corporation
    Inventors: Sui Xiong Cai, Mark B. Anderson, Adam Willardsen, Songchun Jiang, Robert J. Halter, Rachel Slade, Yevgeniya Klimova
  • Enzyme assay and use thereof
    Patent number: 7816099
    Abstract: An assay and kit for determining the activity of an enzyme such as kinase, ATPase and GTPase is disclosed. The assay and kit are useful in drug screening to select modulators of such an enzyme.
    Type: Grant
    Filed: January 9, 2008
    Date of Patent: October 19, 2010
    Assignee: Myrexis, Inc.
    Inventors: Kirill Ostanin, Thomas Hunsaker
  • Polymorphs of 3--(3?,3?-dimethylsuccinyl)betulinic acid di--methyl-D-glucamine
    Patent number: 7799768
    Abstract: The present invention relates to crystalline polymorphs of 3-O-(3?,3?-dimethylsuccinyl)betulinic acid di-N-methyl-D-glucamine salt (“DSB•2NMG)”), pharmaceutical compositions of the same and use of the same as an active pharmaceutical agent in the treatment of HIV related disorders.
    Type: Grant
    Filed: April 12, 2006
    Date of Patent: September 21, 2010
    Assignee: Myrexis, Inc.
    Inventors: Mike H. O'Neill, Gary G. Sweetapple, Randall M. Walker, Arndt Hausherr, Gunter Koch, David E. Martin