Abstract: An endoscope device having a curvable portion and a pivotable lever enclosed within a housing connected to a spring means for returning the trigger and the control wire to a resting position once a user is finished squeezing the trigger. The pivotable lever defines first and second ends connected to an adjustment wire and a control wire respectively. When the trigger is squeezed, the curvable portion curves in a controlled manner from a fully straight configuration.
Abstract: An apparatus and methods for binding an analyte of interest in a sample are provided. The apparatus comprises a substrate with an exposed surface with an compound, that is electrostatically charged or capable of forming hydrogen bonds, provided bound to the solid substrate. A recombinant single chain antibody (scFv) molecule specific for the analyte of interest, having one or more amino acids with charged or hydrogen-bond forming sidechains in a linker polypeptide portion, is bound to the layer on the solid substrate. When the analyte of interest is present in the sample the scFv binds the analyte to the solid substrate. The apparatus can be used with an immunoglobulin layer to detect Fc receptors, so as to detect microorganisms such as Staphylococcus aureus having protein A or protein G.
Type:
Grant
Filed:
February 10, 2011
Date of Patent:
April 3, 2012
Assignees:
Oakland University, Vanderbilt University
Abstract: A composition and method are described for sanitizing or otherwise treating a material such as a non-living surface, living tissue, soil or atmosphere which may be contaminated by a toxin, chemical warfare agent, insect, prion, microorganism or other infectious agent. The composition generally includes an aqueous composition mixture that includes: (a) lower alkanol; (b) an alkalinating agent, and (c) a fatty acid salt and/or ester. The components are present in an effective amount to sanitize (or treat) a material (or modifying a chemical contained thereon) to which the composition is applied. Also described are methods of making the composition.
Abstract: The present invention relates to hard coating of ferrous metal substrates using a laser beam with diamond particles in a metal matrix produced from precursor powders of metals which bond to the diamond particles and to the ferrous substrate. The hard coating is particularly useful for white iron castings for pumps (200) used in piping tar sand and water mixtures.
Type:
Grant
Filed:
January 10, 2008
Date of Patent:
February 21, 2012
Assignees:
Fraunhofer USA, Fraunhofer IWS
Inventors:
Eric Stiles, Thomas Himmer, James E. Herbison, Anja Techel
Abstract: A composition and method are described for sanitizing or otherwise treating a material such as a non-living surface, living tissue, soil or atmosphere which may be contaminated by a toxin, chemical warfare agent, insect, prion, microorganism or other infectious agent. Also described are methods of making the composition.
Abstract: A test kit for detecting an antibiotic or antibiotics containing a ?-lactam ring in a biological fluid is provided. The test kit includes at least one recognition agent, which is a receptor which specifically binds to antibiotics containing a ?-lactam ring and is obtained from Bacillus licheniformis. The test kit further contains at least one reference antibiotic immobilized on a solid support.
Type:
Grant
Filed:
June 14, 2002
Date of Patent:
January 31, 2012
Assignee:
Neogen Corporation
Inventors:
Jacques Degelaen, Benoît Granier, Jean-Marie Frere, Bernard Joris
Abstract: The invention relates to carbon deposition by decomposing gaseous compounds with the aid of the SHF discharge plasma. Said invention ensures a high speed deposition of the high quality diamond films (having a loss-tangent angle ? equal to or less than 3×10?5 on supports whose diameter is equal to or higher than 100 mm. For this purpose, a SHF discharge is initiated in a gas mixture which is arranged in a reaction chamber having a frequency f which is many times higher than a commonly used frequency of 2.45 GHz, for example 30 GHz. In order to localize the plasma, a standing wave is formed near the carrier and plasma layers are formed in the antinodes thereof in such a way that the sizes thereof are adjustable.
Abstract: Methods of binding and detecting a microorganism on a solid substrate. The microorganism is bound on a solid substrate covalently bound to a capture agent having a saccharide moiety. A lectin capable of binding to the microorganism and the saccharide moiety of the capture agent is added to the sample to bind the microorganism on the solid substrate. Further provided are biosensor devices, such as a quartz crystal microbalance (QCM) device or a surface plasmon resonance (SPR) device, that incorporate the solid substrate for the detection of microorganisms.
Abstract: A method is disclosed that generates design profiles and a surface therefrom that promote water drainage from soil in an area of interest. Topographical data describing an initial surface of the area of interest are used to form initial profiles. The method generates the design profiles using the initial profiles and desired design parameters such as minimum slope, maximum slope, optimal slope, maximum depth, optimal depth, starting elevation, ending elevation, rules of curvature, and rules of earth balancing. The method generates design surface profiles so that the cut volumes and fill volumes of the soil are at or near balance as much as possible from the available soil in the area of interest.
Abstract: The present invention relates to an apparatus for loading a barrel of a muzzle loading firearm to provide powder and a projectile at a breach end of the barrel. The apparatus comprises: (i) a handle having a central longitudinal axis and adapted to be gripped by one hand, the handle having an opening between opposed ends along the axis; (ii) a moveable casing having a head and mounted in the opening adjacent one end of the handle and adapted to receive a ramrod of the muzzle loading rifle into the casing; (iii) a retaining means for retaining the casing within the opening, the retaining means mounted on the handle with at least a portion of the retaining means mounted inside the opening; and (iv) a coil spring mounted in the opening inside the handle between the portion of the retaining means mounted in the opening and the head of the casing.
Abstract: Polyazacrown polymers based on the azacrown monomer 1,4,7,10,13,16,21,24-octaazabicyclo[8.8.8]hexacosane (“H6Aza222”) are disclosed. Azacrown monomer units are preferably linked with a suitable linking agent, and the resulting polymers are can absorb mercury from a water stream and form a stable complex therewith. Methods of making and using the polyazacrown polymers are also disclosed. The polymers have a high absorption capacity for and selectivity towards mercury, which properties are useful for the remediation of mercury-contaminated water. The polymers can be regenerated by the efficient removal of the absorbed mercury. Further, the absorbed mercury that is liberated from the polyazacrown polymers can be effectively concentrated and captured to prevent its re-release into the environment.
Type:
Grant
Filed:
February 19, 2008
Date of Patent:
June 28, 2011
Assignee:
Board of Trustees of Michigan State University
Inventors:
Mikhail Y. Redko, James E. Jackson, Volodymyr Tarabara, Julian Taurozzi
Abstract: A prosthetic eye with an iris constructed of a photoresponsive, polymer based element. The photoresponsive element is responsive to light, so that the pupils constrict in the presence of light. The responsiveness of the pupils to light gives the prosthetic eye a more natural appearance.
Abstract: The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.
Abstract: A polyolefin composition containing elastomers (plasticizers), crystalline polypropylene, modified by mixing with polybutene-1 and a coupling agent and a bicyclic dicarboxyl acid salt nucleating agent and/or a lubricant which comprises an unsaturated fatty acid ester which acts as a surface modifier in a molded article is described. The composition is adapted to be used with pigments to make finished molded articles which have an appearance of paint covered by a clear coat and which are scratch resistant and have good low temperature (?30° C.) impact properties.
Abstract: A surface plasmon resonance biosensor device and system are provided. The simplicity of SPR biosensor design allows easy integration with both QCM and electrochemistry techniques, not found in current SPR biosensor devices. In some embodiments, the surface plasmon resonance biosensor device has a dual SPR/QCM sample holder which allows simultaneous detection by both surface plasmon resonance and also quartz crystal microbalance (QCM) techniques. In additional embodiments, the surface plasmon resonance biosensor device and/or the dual SPR/QCM technique can be integrated with electrochemistry techniques by incorporate reference and counter electrodes in the SPR or SPR/QCM sample holder. Methods of using the device and system to determine whether an analyte of interest is present in a sample are also provided.
Abstract: A homopolymer of 1,4-benzodioxepin-3-cyclohexyl-2,5-dione with a Tg of 120° C. Copolymers are also described. The polymers are useful for surgical and other applications where biodegradability is important.
Type:
Grant
Filed:
October 30, 2007
Date of Patent:
April 12, 2011
Assignee:
Board of Trustees of Michigan State University
Inventors:
Gregory L. Baker, Feng Jing, Milton R. Smith, III
Abstract: A process for the treatment of biomass to render structural carbohydrates more accessible and/or digestible using concentrated ammonium hydroxide with or without anhydrous ammonia addition, is described. The process preferably uses steam to strip ammonia from the biomass for recycling. The process yields of monosaccharides from the structural carbohydrates are good, particularly as measured by the enzymatic hydrolysis of the structural carbohydrates. The monosaccharides are used as animal feeds and energy sources for ethanol production.
Type:
Grant
Filed:
September 17, 2007
Date of Patent:
March 29, 2011
Assignee:
Board of Trustees of MICHIGAN STATE UNIVERSITY
Abstract: The present invention provides a detectable heavy duty needle cannula (12) for use in hypodermic syringes and the like. Needle cannula (12) comprises a magnetizable or magnetized stainless steel alloy, which enables needle cannula (12) to be detectable in metal detectors that are commonly used in the meat processing industry to detect broken needle cannulas in the flesh of slaughtered animals. Needle cannula (12) further comprises a sidewall (17) that is thicker than the sidewalls of prior art needle cannulas. The thicker sidewall imparts to needle cannula (12) greater resistance to breakage during the process of injecting animal health products into an animal and greater detectability in a metal detector.
Abstract: Compositions comprising a herbicide wherein it is desired that the compound not be retained by the plant foliage, and a repellant adjuvant, wherein the repellant modifies the surface properties of the composition so that retention of the composition on foliage of a cultivated plant is reduced are described. In particular, the herbicide composition comprises a repellant adjuvant that is an aqueous solution of an alkyltrialkoxysilane such as methyltrimethoxysilane and a water soluble silane coupling agent such as N-(2-aminoethyl) -3-aminopropyltrimethoxysilane or an aqueous solution of an organosiliconate such as sodium methyl siliconate. Methods are described for using these compositions to prevent weeds without injury to cultivated plants, which plants include crop plants, food plants, turfgrass, ornamental plants, and garden plants.
Type:
Grant
Filed:
September 10, 2004
Date of Patent:
March 8, 2011
Assignees:
Board of Trustees of MICHIGAN STATE UNIVERSITY, Dow Corning Corporation
Inventors:
Donald Penner, Christy L. Sprague, Richard F. Burow
Abstract: Magnetic stainless steel needles are detectable in processed meat. The previous non magnetic versions, made of 304 stainless steel, aren't. Disposable hypodermic needles made from martensitic and ferritic stainless steel are easily detectable at the smallest size. Needles are conveniently made from 420 martensitic stainless steel or 430 ferritic stainless steel.