Patents Represented by Attorney, Agent or Law Firm Incyte Genomics, Inc.
  • Human galactosyltranferases
    Patent number: 6649737
    Abstract: The invention provides human galactosyltransferases (HUGA) and polynucleotides which identify and encode HUGA. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HUGA.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: November 18, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Purvi Shah, Chandra Patterson
  • RVP-1 variant differentially expressed in Crohn's disease
    Patent number: 6590089
    Abstract: The invention provides a mammalian cDNA which encodes a mammalian an RVP-1 variant. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of Crohn's disease. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: July 8, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Lynn E. Murry, Jennifer L. Hillman, Y. Tom Tang, Chandra Patterson
  • Aquaporin-8 variant
    Patent number: 6566066
    Abstract: The invention provides a mammalian cDNA which encodes a mammalian AQP8V. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of pancreatic disorders, particularly type I diabetes. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: May 20, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Michael G. Walker, Wayne Volkmuth, Tod M. Klinger
  • Human lysophosphatidic acid acyltransferase
    Patent number: 6558914
    Abstract: The invention provides a human lysophosphatidic acid acyltranferase (HLPAAT) and polynucleotides which identify and encode HLPAAT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HLPAAT.
    Type: Grant
    Filed: September 2, 1999
    Date of Patent: May 6, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley
  • Human transferase proteins
    Patent number: 6558935
    Abstract: The invention provides human transferase proteins (TRNSFS) and polynucleotides which identify and encode TRNSFS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provide methods for diagnosing, treating, or preventing disorders, associated with expression of TRNSFS.
    Type: Grant
    Filed: March 12, 2002
    Date of Patent: May 6, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn, Preeti Lal, Henry Yue, Jennifer L. Hillman, Yalda Azimzai
  • Human selenoprotein
    Patent number: 6545129
    Abstract: The present invention provides a human selenoprotein (HSEL) and polynucleotides which identify and encode HSEL. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HSEL and a method for producing HSEL. The invention also provides for agonists, antibodies, or antagonists specifically binding, HSEL, and their use, in the prevention and treatment of diseases associated with expression of HSEL. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HSEL for the treatment of diseases associated with the expression of HSEL. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HSEL.
    Type: Grant
    Filed: September 10, 1999
    Date of Patent: April 8, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Detection of genes regulated by EGF in breast cancer
    Patent number: 6544742
    Abstract: The present invention relates to a combination comprising a plurality of polynucleotide probes that are modulated in response to EGF and which are associated with breast cancer, and which may be used in their entirety or in part as to diagnose, to stage, to treat, or to monitor the treatment of a subject with a breast cancer.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: April 8, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Mary Faris, David G. Streeter
  • ATP synthase subunits
    Patent number: 6531575
    Abstract: The present invention provides two ATP synthase subunits (designated individually as Asy-1 and Asy-2, and collectively as Asy) and polynucleotides which identify and encode Asy. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding Asy and a method for producing Asy. The invention also provides for use of Asy and agonists, antibodies, or antagonists specifically binding Asy, in the prevention and treatment of diseases associated with expression of Asy. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding Asy for the treatment of diseases associated with the expression of Asy. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding Asy.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: March 11, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Surya K. Goli
  • Maternally transcribed protein
    Patent number: 6527689
    Abstract: The invention provides a human maternally transcribed protein (HMTP) and polynucleotides which identify and encode HMTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HMTP.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: March 4, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley
  • Human RNA binding process
    Patent number: 6524579
    Abstract: The invention provides human RNA binding proteins (RNABP) and polynucleotides which identify and encode RNABP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of RNABP.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: February 25, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • DNA encoding sparc-related proteins
    Patent number: 6524799
    Abstract: The invention provides mammalian cDNAs which encode mammalian SPARC-related proteins. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of atherosclerosis and cell proliferative disorders. The invention additionally provides expression vectors and host cells for the production of the proteins and transgenic model systems.
    Type: Grant
    Filed: August 16, 2000
    Date of Patent: February 25, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Michael G. Walker, Randi E. Krasnow
  • Human peptidyl-prolyl isomerases
    Patent number: 6524838
    Abstract: The invention provides human peptidyl-prolyl isomerases (HPPIP) and polynucleotides which identify and encode HPPIP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HPPIP.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: February 25, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Preeti Lal, Neil C. Corley, Chandra Patterson, Mariah R. Baughn
  • Down syndrome critical region 1-like proteins
    Patent number: 6524819
    Abstract: The invention provides a mammalian nucleic acid molecule and fragments thereof. It also provides for the use of the mammalian nucleic acid molecule for the characterization, diagnosis, evaluation, treatment, of conditions, diseases and disorders associated with gene expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecule.
    Type: Grant
    Filed: July 11, 2000
    Date of Patent: February 25, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Jeanne F. Loring, Debora W. Tingley, Carla M. Edwards, David G. Streeter
  • Human hydrolase-like molecules
    Patent number: 6518029
    Abstract: The invention provides human hydrolase-like molecules (HHLM) and polynucleotides which identify and encode HHLM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HHLM.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: February 11, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Preeti Lal, Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Purvi Shah
  • Human fatty acid beta-oxidation enzymes
    Patent number: 6511833
    Abstract: The invention provides human fatty acid beta-oxidation enzymes (HUFA) and polynucleotides which identify and encode HUFA. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUFA.
    Type: Grant
    Filed: January 11, 2000
    Date of Patent: January 28, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Karl J. Guegler, Neil C. Corley, Y. Tom Tang, Purvi Shah
  • Nucleic acids encoding GTPase activating proteins
    Patent number: 6509155
    Abstract: The invention provides mammalian nucleic acid molecules and fragments thereof. It also provides for the use of the mammalian nucleic acid molecules for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with cell signaling, the immune system, and cell proliferation, particularly colon cancer. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecules.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: January 21, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Tod M. Klinger, Elizabeth A. Stewart, Henry Yue, Mariah R. Baughn
  • Human glutathione-S-transferase
    Patent number: 6506571
    Abstract: The invention provides a human glutathione-S-transferase (HGST) and polynucleotides which identify and encode HGST. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HGST.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: January 14, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Henry Yue, Neil C. Corley, Purvi Shah
  • Human anion channel
    Patent number: 6503733
    Abstract: The present invention provides a novel human anion channel (NANCH) and polynucleotides which identify and encode NANCH. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NANCH and a method for producing NANCH. The invention also provides for agonists, antibodies, or antagonists specifically binding NANCH, and their use, in the prevention and treatment of diseases associated with expression of NANCH. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NANCH for the treatment of diseases associated with the expression of NANCH. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NANCH.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: January 7, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Microtubule-associated protein
    Patent number: 6503708
    Abstract: The invention provides a human microtubule-associated protein (HMAP) and polynucleotides which identify and encode HMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HMAP.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: January 7, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Neil C. Corley
  • Molecule associated with apoptosis
    Patent number: 6500642
    Abstract: The invention provides a mammalian cDNA which encodes a mammalian MAPOP-3. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of breast adenocarcinoma. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: December 31, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Henry Yue, Chandra Patterson, Neil C. Corley, Karl J. Guegler