Patents Represented by Attorney, Agent or Law Firm Incyte Pharmaceuticals, Inc.
  • Ubiquitin-like conjugating protein
    Patent number: 5968747
    Abstract: The invention provides a human ubiquitin-like conjugating protein (UBCLE) and polynucleotides which identify and encode UBCLE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of UBCLE.
    Type: Grant
    Filed: December 12, 1997
    Date of Patent: October 19, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Neil C. Corley
  • Human glutaredoxin .beta.
    Patent number: 5968798
    Abstract: The invention provides a human glutaredoxin .beta. (GRX.beta.) and polynucleotides which identify and encode GRX.beta.. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of GRX.beta..
    Type: Grant
    Filed: August 14, 1997
    Date of Patent: October 19, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Purvi Shah
  • Regulator of gene transcription
    Patent number: 5965706
    Abstract: The present invention provides a human regulator of gene transcription (HRGT) and polynucleotides which encode HRGT. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of HRGT.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli, David G. Streeter
  • Antibody to serine protease precursor
    Patent number: 5965711
    Abstract: The present invention provides a human serine protease precursor (HSPP) and polynucleotides which encode HSPP. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of HSPP.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Purvi Shah
  • Two novel human cathespin proteins
    Patent number: 5965129
    Abstract: The present invention provides two novel human cathepsin proteins (HCPs) and polynucleotides encoding HCPs. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding HCPs. The invention also provides for the production and use of antibodies to HCPs in pharmaceutical compositions for the treatment of disease processes that include cancers, inflammation, metastasis and peptide and proenzyme processing. In addition, the invention provides for the production and use of inhibitors of HSPs in pharmaceutical compositions for the treatment of diseases. The invention also describes diagnostic assays which utilize the polynucleotide to hybridize with the transcripts encoding HCPs. The invention also provides for the use of antisense molecules in pharmaceutical compositions as therapeutics in cancers, inflammation, metastasis and peptide and proenzyme processing.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Roger Coleman
  • Serine/threonine protein kinase
    Patent number: 5965365
    Abstract: The present invention provides a human growth factor receptor binding protein (HSTPK) and polynucleotides which encode HSTPK. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for producing HSTPK and for treating disorders associated with expression of HSTPK.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Preeti Lal
  • Human succinyl-coenzyme a synthetase holoenzyme
    Patent number: 5965369
    Abstract: The invention provides human succinyl-CoA synthetase holoenzyme (SCSH) and polynucleotides which identify and encode SCSH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of SCSH.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Preeti Lal, Neil C. Corley, Chandra Patterson
  • Human importin alpha homolog
    Patent number: 5965394
    Abstract: The invention provides a human importin alpha homolog (IMPAH) and polynucleotides which identify and encode IMPAH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of IMPAH.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Neil C. Corley, Purvi Shah
  • Human lysophospholipase
    Patent number: 5965423
    Abstract: The invention provides a human lysophospholipase (NHLP) and polynucleotides which identify and encode NHLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of NHLP.
    Type: Grant
    Filed: February 12, 1998
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Lynn E. Murry
  • Maternally transcribed protein
    Patent number: 5965395
    Abstract: The invention provides a human maternally transcribed protein (HMTP) and polynucleotides which identify and encode HMTP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HMTP.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: October 12, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley
  • Human glutathione-S-transferase
    Patent number: 5962231
    Abstract: The invention provides a human glutathione-S-transferase (HGST) and polynucleotides which identify and encode HGST. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HGST.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Neil C. Corley, Purvi Shah
  • Human RNA-binding protein
    Patent number: 5962226
    Abstract: The present invention provides a human RNA bind-protein (HRNABP) and polynucleotides which identify and encode HRNABP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HRNABP and a method for producing HRNABP. The invention also provides for antagonists or antibodies specifically binding HRNABP, and their use, in the prevention and treatment of diseases associated with expression of HRNABP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HRNABP for the treatment of diseases associated with the expression of HRNABP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HRNABP.
    Type: Grant
    Filed: November 26, 1996
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Polynucleotides encoding a neuronal extracellular matrix protein
    Patent number: 5962261
    Abstract: The present invention provides a human neuronal extracellular matrix protein (HNEP) and polynucleotide which encode HNEP. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for treating disorders associated with expression of HNEP.
    Type: Grant
    Filed: April 28, 1997
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Purvi Shah
  • ATP synthase Fo subunit
    Patent number: 5962646
    Abstract: The present invention provides a human ATP synthase d subunit (ASYSD) and polynucleotides which encode ASYSD. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides to methods for producing ASYSD and for treating disorders associated with expression of ASYSD.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Human heat shock 27 like protein
    Patent number: 5962262
    Abstract: The invention provides a new human heat shock 27 like protein, (HSP27P) and polynucleotides which identify and encode HSP27P. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HSP27P.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Purvi Shah
  • Protein kinase molecules
    Patent number: 5962232
    Abstract: The invention provides human protein kinase molecules (HPKM) and polynucleotides which identify and encode HPKM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HPKM.
    Type: Grant
    Filed: January 30, 1998
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Preeti Lal, Ingrid E. Akerblom, Purvi Shah, Neil C. Corley, Karl J. Guegler
  • Human kallikrein
    Patent number: 5962300
    Abstract: The present invention provides a human tumor suppressor (HKALL) and polynucleotides which identify and encode HKALL. The invention also provides expression vectors and host cells, agonists, antibodies, or antagonists. The invention provides methods for treating diseases associated with expression of HKALL.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal
  • Human N-acetylneuraminate lyase
    Patent number: 5962302
    Abstract: The invention provides a human N-acetylneuraminate lyase (HNANL) and polynucleotides which identify and encode HNANL. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HNANL.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: October 5, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Neil C. Corley
  • Cell junction PDZ protein
    Patent number: 5958731
    Abstract: The invention provides a human cell junction PDZ protein (CJPDZ) and polynucleotides which identify and encode CJPDZ. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CJPDZ.
    Type: Grant
    Filed: September 11, 1998
    Date of Patent: September 28, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Janice Au-Young, Chandra Patterson
  • Human protein tyrosine kinase
    Patent number: 5958405
    Abstract: The present invention provides a novel protein tyrosine kinase (HPTYK) and polynucleotides which identify and encode HPTYK. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPTYK and a method for producing HPTYK. The invention also provides pharmaceutical compositions containing HPTYK or antagonists to HPTYK, and for the use of these compositions in the treatment of diseases associated with the expression of HPTYK. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPTYK for the treatment of diseases associated with the expression of HPTYK. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, to hybridize to the genomic sequence or transcripts of polynucleotides encoding HPTYK or antibodies which specifically bind to HPTYK.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: September 28, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventor: Surya K. Goli