Patents Represented by Law Firm Irons and Sears
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Patent number: 4460694Abstract: A novel purification scheme is described for obtaining two novel and useful forms of bovine glycoprotein (BGP) from bovine erythrocytes, each of which acts as an antigen in testing for the presence of the heterophile antibodies of human infectious mononucleosis.The first, or partially purified, BGP is obtained from crude BGP and contains about 10% by weight of a complex glycoplipid. It forms a single band upon gel electrophoresis at pH 7.0 under specified conditions.The second, or homogeneous, BGP is obtained by removing essentially all of the complex glycolipid. It forms substantially a single band upon gel electrophoresis at pH 7.0 under specified conditions.Both forms may be used to detect or quantify hemagglutination inhibition of a test sample (and hence to determine the presence or extent to mononucleosis infection) in a glass slide test wherein the partially purified or homogeneous BGP is carried on latex or synthetic resin beads.Type: GrantFiled: March 9, 1982Date of Patent: July 17, 1984Assignee: University of MiamiInventor: Mary A. Fletcher
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Patent number: 4439058Abstract: An artificial seaweed, or "asymmetric seaweed", system for preventing shoreline erosion and/or causing sand accretion on beaches under wave action.Type: GrantFiled: February 8, 1982Date of Patent: March 27, 1984Assignee: University of MiamiInventor: Bernard J. Le Mehaute
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Patent number: 4426295Abstract: A process is provided which permits the rapid concentration and collection of cells in body fluid with minimal need for centrifugation and without filtration or sediment flotation, while also permitting the collection of cells from the fluid in an essentially monolayer arrangement with essentially no cell distortion. The apparatus used in this process comprises an elongated receptacle or chamber having, at one end, an outlet opening through which body fluid containing cells to be collected can be introduced, e.g., by means of a syringe, and, interposed between the inlet opening and an outlet opening at the other end of the chamber, a filter, e.g., a microporous filter.Type: GrantFiled: September 28, 1981Date of Patent: January 17, 1984Inventors: Deborah A. Evans, Lisbeth E. Shelley
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Patent number: 4398174Abstract: A fuel consumption signalling system for signalling both efficient and inefficient fuel consumption conditions in the engine of a motor vehicle is herein disclosed. The system comprises an alarm circuit connected in series with an indicator circuit including an indicator light connected in parallel with a vacuum operated switch pneumatically connected to the engine manifold. An electric potential sufficient to actuate the alarm circuit, but insufficient to actuate both the indicator light and the alarm circuit is applied across the series connected indicator and alarm circuits. When the engine is consuming fuel efficiently, the vacuum switch is open, and the electric potential is divided between the indicator circuit and the alarm circuit. The divided potential is sufficient to illuminate the indicator light, but insufficient to actuate the alarm circuit.Type: GrantFiled: November 17, 1980Date of Patent: August 9, 1983Inventor: Raymond P. Smith, Jr.
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Patent number: 4383936Abstract: A method for unloading alkali earth metal carbonates, in slurry form, from bulk storage is described. A specially formulated alkali earth metal carbonate composition containing an ultra-hydrophilic dispersant is also described.Type: GrantFiled: May 10, 1971Date of Patent: May 17, 1983Assignee: Chemical Products CorporationInventors: Arvel O. Franz, John L. Gray
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Patent number: 4347525Abstract: In the label printing system of the present invention, a strip of adhesive-backed label stock capable of receiving a latent charge image and having a releasable backing layer is drawn continuously from a supply reel and passed successively through an electrostatic print head, a developer, a pressure fixer, and a rotary die or butt cutter for separating the printed stock into individual labels on the uncut releasable backing layer. The latent imaging of each label at the electrostatic print head is carried out at defined discrete locations on the label stock. These locations may be defined in response to a synchronization signal produced by an angular position detector cooperating with the rotary cutter. The synchronization signal is indicative of a predetermined instantaneous rotational orientation of the cutting elements on the rotary cutting member, thereby insuring that the printed label indicia are properly centered within the label edges after die or butt cutting.Type: GrantFiled: September 25, 1980Date of Patent: August 31, 1982Assignee: Markem CorporationInventors: Robert A. Moore, Bruce K. Norlund, Harold S. Kontrovitz, Clayton B. Robbins, Jeffrey B. Brooks
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Patent number: 4340532Abstract: Two component adhesive formulations are described that can be mixed to form compositions containing a curable liquid resin binder and filler. The liquid resin binder comprises from about 1% to about 60% of a lower alkoxy, lower alkyl methacrylate comprising methoxyethyl methacrylate, and from about 40% to about 99% of a polyunsaturated agent selected from the group consisting of aliphatic or aromatic diacrylates or dimethacrylates or mixtures thereof, the percentages being by weight based on the liquid resin binder. The filler forms up to 80% by weight of the adhesive composition and consists of finely divided inorganic filler, finely divided organic filler that may be soluble in the liquid resin binder, and mixtures thereof. The preferred compositions are useful as orthodontic adhesives and contain from about 10% to about 50% by weight of the liquid resin binder of methoxyethyl methacrylate.Type: GrantFiled: April 11, 1980Date of Patent: July 20, 1982Assignee: Lee Pharmaceuticals, Inc.Inventors: Henry L. Lee, Jr., Giovanni Nolet
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Patent number: 4340529Abstract: In an adhesive having two curable components designed to be coated in separate layers on one or more of two surfaces to be joined, and cured upon contact of the layers with each other, one component is a curable liquid primer having a viscosity of at least 800 cps but no more than about 50,000 cps at 23.degree. C., and the second component is a paste having a viscosity of at least 100,000 cps at 23.degree. C. The primer is formulated with a curable liquid monomer component of which at least 30% is an alkoxy alkyl methacrylate, any balance of curable monomer in the primer comprising monomer that is capable of copolymerizing with the first-named monomer and/or cross-linking with it. Also covers the method for joining together two irregular surfaces, utilizing such an adhesive formulation. Particularly intended for orthodontic adhesive applications.Type: GrantFiled: April 11, 1980Date of Patent: July 20, 1982Assignee: Lee Pharmaceuticals, Inc.Inventors: Henry L. Lee, Jr., Giovanni Nolet
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Patent number: 4327178Abstract: Substrates and method for the assay of urinary kallikrein are provided. The substrates have the general formula ##STR1## wherein R is H, acetyl, benzoyl, cyclopentylcarbonyl, succinyl, R.sub.1 --Ser.sub.1 or R.sub.1 --Phe--Ser where R.sub.1 is H, acetyl, benzoyl, cyclopentylcarbonyl or succinyl,X is H, tritium, 3-iodo or 4-iodo, andn is 0 or 1.Radioactive label may be incorporated in the anilide or benzylamide moiety. Hydrolysis catalyzed by urinary kallikrein yields labeled aniline or benzylamine as product.The assay method includes mixing the enzyme with substrate in a buffered solution, pH 7.5-10.5, the substrate being present preferably at a concentration substantially below K.sub.m. After incubating to allow the reaction to proceed, the reaction is terminated and the radioactive hydrolysis product is separated and counted.Also disclosed are compounds of the type ##STR2## wherein R, R.sub.1 and n are as defined above. X is 3--OH or 4--OH. Y.sub.1 is 3-iodo if X is 4--OH or 6-iodo if X is 3--OH. Y.sub.Type: GrantFiled: March 31, 1981Date of Patent: April 27, 1982Assignee: University of MiamiInventors: James W. Ryan, Alfred Chung
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Patent number: 4324243Abstract: An apparatus and process for aspirating and evacuating a pneumatically operated surgical instrument, such as an intraocular vitrectomy unit having a reciprocating blade for severing unwanted intraocular tissues, is disclosed herein. The apparatus includes a collapsible conduit pneumatically connected to a receptacle for conducting an aspirating negative pressure to the surgical instrument and evacuating material received therefrom into the receptacle. A pneumatically operated clamping means functions both to terminate the application of negative pressure through the collapsible conduit and to eliminate residual negative pressure within the conduit between the blocked portion of the conduit and the surgical instrument.Type: GrantFiled: November 28, 1979Date of Patent: April 13, 1982Inventors: Maxwell A. Helfgott, Gerald N. Helfgott
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Patent number: 4323647Abstract: A novel separation technique is described that is particularly useful for effecting separations in enzyme immunoassay procedures. A mixture, in an aqueous liquid vehicle, of (1), ligand-enzyme conjugate, and of (2), the conjugate bound through its ligand moiety to a receptor, is brought into contact with an insoluble, immobilized pseudo-substrate material, to which the enzyme normally binds. Free conjugate binds and becomes insoluble. Bound conjugate remains in the liquid phase. The ligand may be an antigen and the receptor, the antibody to the antigen.This separation technique makes feasible several sensitive immunoassay procedures. The material to be assayed may be, for example, rubella virus; hepatitis B surface antigen; gonorrhea antigen; the antibody to any of the foregoing; a general antibody, i.e., an immunoglobulin; a hormone such as choriomammotropin; a steroid, hapten, or the like.Type: GrantFiled: October 15, 1980Date of Patent: April 6, 1982Assignee: University of MiamiInventors: Nobuo Monji, Albert Castro
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Patent number: 4321777Abstract: This pane comprises at least one sheet of plastics material, for example a polycarbonate, which has a high resistance to impacts and is interposed between two sheets of glass or the like. A film of a transparent fluid is interposed between the sheet of plastics material and each adjacent sheet of glass. A sealing element for the fluid extends around the periphery of the pane.Application as a bullet-proof pane to wind screens and windows of automobile vehicles, to glass, windows and doors of buildings, etc . . .Type: GrantFiled: January 28, 1980Date of Patent: March 30, 1982Assignee: Brink's France S.A.Inventors: Jacques Sauret, Gerard Grosse
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Patent number: 4319405Abstract: A leveling instrument for use in the building and construction trades comprises a sighting telescope embraced by one or more support members for sighting along horizontal distances, a spirit level frame having at least one bubble level tube mounted therein for indicating the horizontal alignment of the sighting telescope, and a leveling platform having a plurality of vertically adjustable legs for leveling the instrument on a support surface. The aforementioned components are maintained in relative alignment by means of flat planar mating surfaces without rigid mechanical connection therebetween in order to facilitate rapid assembly and disassembly of the instrument and compact storage. The sighting telescope includes a pair of intersecting crosshairs which may be manually adjusted in elevation, making it possible to sight along non-horizontal lines without physically tilting the leveling instrument as a whole.Type: GrantFiled: January 31, 1980Date of Patent: March 16, 1982Inventor: Orville E. Price
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Patent number: 4314560Abstract: A powered handpiece for use in endophthalmic surgery comprises a projecting tubular surgical instrument including an inner tubular member slidably received within a coaxial outer tubular member for reciprocation therein, a pneumatic actuator for imparting reciprocation to the inner tubular member, and a coupling member interposed between the actuator and the surgical instrument for transmitting reciprocating motion from the actuator to the inner tubular member. The coupling member has a recessed configuration permitting a flexible suction or infusion tube to be connected to the proximal end of the inner tubular member. The pneumatic actuator, coupling member, and proximal portion of the tubular surgical instrument are received in tandem arrangement by a housing having a side opening for the flexible suction or infusion tube and a separable anterior section for permitting interchangeability among different surgical instruments.Type: GrantFiled: November 28, 1979Date of Patent: February 9, 1982Inventors: Maxwell A. Helfgott, Gerald N. Helfgott
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Patent number: 4308185Abstract: Epoxy resin is reacted with a terminating agent to eliminate at least part of the epoxide groups of the resin and form modified resin. The epoxy resin or such modified resin is also reacted with addition polymerizable monomer at elevated temperature in the presence of at least 3% of benzoyl peroxide based on the weight of such monomer. Generally the latter reaction is done at about 110.degree. C. to about 120.degree. C. These two reactions can be performed in any desired sequence, or simultaneously. The final reaction mixture produced contains:(a) graft polymer;(b) ungrafted, modified resin; and(c) ungrafted addition polymer, formed associativelywith the graft polymer. The invention is useful for making coating compositions. The compositions have good weather resistance and are particularly useful for making sanitary coatings for cans for foods and beverages, especially for beer.Type: GrantFiled: May 14, 1979Date of Patent: December 29, 1981Assignee: SCM CorporationInventors: James M. Evans, Vincent W. Ting
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Patent number: 4298922Abstract: A rotatably adjustable light shield for shielding and suspending a portable trouble lamp is disclosed herein. The light shield generally comprises a cylindrical shield member, a mounting means attached to the bottom end of the shield member for mounting the shield member onto a trouble lamp, and a rotatably adjustable suspension means mounted on top of the shield member for providing a rotatably adjustable suspension mount for the shield. The suspension mount includes a plate having a circular array of detent cavities, a detent ball retainer rotatably mounted over the plate and having at least one detent ball receivable into each of the detent cavities in the plate, and a suspension hook assembly mounted onto the detent ball retainer for suspending the trouble lamp.Type: GrantFiled: November 2, 1979Date of Patent: November 3, 1981Inventor: Cret E. Hardwick
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Patent number: 4288136Abstract: The cupboard is made from a framework comprising four tubular uprights having a square section and two rectangular or square frames. The sides of the frames are tubes having the same square section as the uprights. In the corners of each frame, the adjacent tubular members are assembled by means of oblique welded gussets. The latter permit the assembly with the uprights engaged in recesses of the frames by means of screws. The side panels are locked to the framework by a roof-cover which has folded edge portions which overlap the upper end of the panels.Type: GrantFiled: August 22, 1979Date of Patent: September 8, 1981Inventor: Gerard Le Mer
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Patent number: 4287819Abstract: The source of vacuum comprises a tubular body in which a piston which is combined with a piston rod is axially slidable. A seal is interposed between the rod and the body where the rod extends out of the body. A suction orifice is provided which is on the axis of or in the vicinity of the axis of the body and parallel to the axis. An arrangement is provided for holding the body and urging the piston to one end of the body in one hand. A communication passage is provided for putting the suction orifice in communication with a chamber defined between the piston and the body when the piston is depressed relative to the body.Type: GrantFiled: November 2, 1978Date of Patent: September 8, 1981Inventor: Andre A. C. Emerit
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Patent number: D264450Type: GrantFiled: March 26, 1979Date of Patent: May 18, 1982Inventor: Raymond P. Smith, Jr.
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Patent number: D267419Type: GrantFiled: May 1, 1980Date of Patent: December 28, 1982Inventor: Gene Komarnicki